{"id":"W350335477","doi":"10.1023/a:1021657220843","title":"Oxidative stress-induced apoptosis in dividing fibroblasts involves activation of p38 MAP kinase and over-expression of Bax: Resistance of quiescent cells to oxidative stress","year":2003,"lang":"en","type":"article","venue":"APOPTOSIS","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Innovation Trust; Life Technologies Corporation","keywords":"Oxidative stress; Cell biology; Apoptosis; p38 mitogen-activated protein kinases; Mitogen-activated protein kinase; Oxidative phosphorylation; Kinase; Chemistry; Biology; Protein kinase A; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000253545,0.0003282533,0.0003136368,0.0003604515,0.0004142847,0.0004059906,0.0002677201,0.0002788898,0.00186666],"category_scores_gemma":[0.0001568109,0.0002104711,0.0003198668,0.0002865635,0.0002439424,0.0004760355,0.0002091109,0.0006116017,0.0003272219],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002585474,"about_ca_system_score_gemma":0.0001795526,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004183143,"about_ca_topic_score_gemma":0.0005034597,"domain_scores_codex":[0.9998442,0.00002114268,0.00002224287,0.00002255556,0.00004836802,0.00004134766],"domain_scores_gemma":[0.9998505,0.00002846235,0.00002937853,0.00003015915,0.00002428107,0.00003723022],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002366699,0.00002514821,0.0002762313,0.00004123006,0.000004538537,0.00012148,0.00003657222,0.00000788016,0.9976274,0.0001330769,0.00003069202,0.001459101],"study_design_scores_gemma":[0.00003080008,0.000280256,0.009858598,0.000004655016,0.00001556935,0.00124817,0.00007061097,0.0002040089,0.9865621,0.0001676097,0.001553065,0.000004650942],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9899271,0.003880156,0.004033911,0.0002584578,0.00006919541,0.00004195153,0.0003389934,0.0000919742,0.001358359],"genre_scores_gemma":[0.992835,0.002056324,0.00180987,0.00004903596,0.00003454655,0.00004517602,0.0003598556,0.00001275192,0.002797494],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00186666,"threshold_uncertainty_score":0.0062446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01149551728413344,"score_gpt":0.2403478706772433,"score_spread":0.2288523533931098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}