{"id":"W350335477","doi":"10.1023/a:1021657220843","title":"Oxidative stress-induced apoptosis in dividing fibroblasts involves activation of p38 MAP kinase and over-expression of Bax: Resistance of quiescent cells to oxidative stress","year":2003,"lang":"en","type":"article","venue":"APOPTOSIS","topic":"Cell death mechanisms and regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":73,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Windsor","funders":"Natural Sciences and Engineering Research Council of Canada; Ontario Innovation Trust; Life Technologies Corporation","keywords":"Oxidative stress; Cell biology; Apoptosis; p38 mitogen-activated protein kinases; Mitogen-activated protein kinase; Oxidative phosphorylation; Kinase; Chemistry; Biology; Protein kinase A; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001557498,0.0001832055,0.0002874183,0.0001415814,0.00004048227,0.000008266186,0.0001064762,0.0001649517,0.00001359224],"category_scores_gemma":[0.00007224134,0.0001744945,0.00006563925,0.0002117449,0.00005331638,0.0000203562,0.0001021733,0.00006215251,2.274879e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002722987,"about_ca_system_score_gemma":0.00003779211,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001313644,"about_ca_topic_score_gemma":0.00009918275,"domain_scores_codex":[0.9987206,0.0001288122,0.0003988369,0.0003599606,0.0002101251,0.0001816918],"domain_scores_gemma":[0.9991316,0.00004789987,0.0003506588,0.0002798214,0.0001240164,0.00006605734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00016311,0.0001721937,0.002471199,0.0002539382,0.00003079775,7.154876e-8,0.0006044932,0.0001816948,0.9952005,0.0002814639,0.00005759521,0.0005830061],"study_design_scores_gemma":[0.0005547131,0.0002782728,0.003283933,0.0006535506,0.00001837076,3.715028e-8,0.001185332,0.00001052709,0.9936768,0.00009632761,0.00007606186,0.0001660051],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981262,0.0001435627,0.001129741,0.00002535551,0.00006287808,0.0003550205,0.00007898195,0.000003515446,0.00007475102],"genre_scores_gemma":[0.9975477,0.0001698411,0.002099215,0.00001081258,0.00001778553,0.00002014127,0.00006420889,0.00001579518,0.00005447316],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001523568,"threshold_uncertainty_score":0.7115679,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01149551728413344,"score_gpt":0.2403478706772433,"score_spread":0.2288523533931098,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}