{"id":"W40002982","doi":"10.1139/y05-117","title":"Calcium signaling in the nucleusThis paper is one of a selection of papers published in this Special Issue, entitled The Nucleus: A Cell Within A Cell.","year":2006,"lang":"en","type":"review","venue":"Canadian Journal of Physiology and Pharmacology","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":46,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; Fogarty International Center; National Institutes of Health","keywords":"Nucleus; Second messenger system; Inositol; Cell biology; Cytosol; Biology; Calcium; Calcium signaling; Signal transduction; Receptor; Chemistry; Neuroscience; Biochemistry; Enzyme","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004455222,0.0009359524,0.001235376,0.001710898,0.0005241915,0.001329016,0.0007727278,0.001226948,0.00592482],"category_scores_gemma":[0.0003954204,0.0002164254,0.0002631525,0.002152419,0.0005551867,0.001801207,0.0006361879,0.001129849,0.007041039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009180589,"about_ca_system_score_gemma":0.001435295,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001173323,"about_ca_topic_score_gemma":0.001888689,"domain_scores_codex":[0.9998379,0.00001647893,0.00001812672,0.00003387797,0.00007799958,0.00001572938],"domain_scores_gemma":[0.9998123,0.00004230145,0.00002148551,0.000006464867,0.00007872149,0.00003886919],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007731171,0.00004606945,0.0001368187,0.007573663,0.00002870265,0.0003805307,0.00009238082,0.0003067661,0.006587848,0.006421523,0.07116302,0.9071853],"study_design_scores_gemma":[0.000005400579,0.00002680183,0.000231638,0.0005315548,0.00001392973,0.0006039808,0.0000308428,0.00002496879,0.0006405309,0.0009242937,0.9969578,0.000008235434],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001968668,0.9932447,0.0002760276,0.0007310136,0.001861523,0.000008432978,0.0000290136,0.00001946186,0.003633004],"genre_scores_gemma":[0.0006990549,0.9942716,0.0002830021,0.0002262197,0.0005664615,0.000005884139,0.00003607847,0.000003377904,0.003908313],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00592482,"threshold_uncertainty_score":0.01982051,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01631606320424187,"score_gpt":0.2708357916951078,"score_spread":0.2545197284908659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}