{"id":"W41349291","doi":"10.1007/978-0-306-47593-1_7","title":"Apolipoprotein E: A Novel Therapeutic Target for the Treatment of Alzheimer’s Disease","year":2002,"lang":"en","type":"book-chapter","venue":"Advances in behavioral biology","topic":"Alzheimer's disease research and treatments","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; Douglas Mental Health University Institute","funders":"","keywords":"Apolipoprotein E; Allele; Internal medicine; Endocrinology; Alzheimer's disease; Biology; Neuroscience; Disease; Medicine; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00005145964,0.0004382402,0.0007522447,0.0001686376,0.00007196175,0.0000049767,0.000155106,0.0002341959,0.0004238006],"category_scores_gemma":[0.000006856159,0.0002623509,0.0004292543,0.00004381919,0.0005391113,0.00005358516,0.00002863315,0.0001564897,0.00002740216],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001530296,"about_ca_system_score_gemma":0.0001551456,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006905208,"about_ca_topic_score_gemma":0.00003036321,"domain_scores_codex":[0.9984108,0.00002073994,0.0004287101,0.0005028322,0.0001854717,0.0004514824],"domain_scores_gemma":[0.9987291,0.000139105,0.0002125779,0.0005861228,0.0001030938,0.0002300473],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.006108625,0.009667465,0.02231834,0.0002016445,0.01061008,0.0003357016,0.0001690502,0.00001433001,0.0002027585,0.04010505,0.00009572064,0.9101712],"study_design_scores_gemma":[0.01933168,0.02762442,0.007403725,0.0005905244,0.01812427,0.0000431327,0.00004672612,0.0001516584,0.001270545,0.03650566,0.8876015,0.001306147],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.00201035,0.9803049,0.0001435932,0.0005738033,0.0003659987,0.007325541,0.003262491,0.00005558891,0.005957753],"genre_scores_gemma":[0.8132223,0.1533742,0.002668683,0.0002416276,0.000759575,0.004780931,0.003194602,0.0002905044,0.0214675],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.9088651,"threshold_uncertainty_score":0.9999829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1053334057215873,"score_gpt":0.3969905159232552,"score_spread":0.2916571102016679,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}