{"id":"W4200000072","doi":"10.17879/freeneuropathology-2021-3679","title":"Friedreich cardiomyopathy is a secondary desminopathy","year":2021,"lang":"en","type":"article","venue":"PubMed","topic":"Genetic Neurodegenerative Diseases","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kinexus Bioinformatics Corporation (Canada); University of British Columbia","funders":"","keywords":"Desmin; Frataxin; Biology; Cardiomyopathy; Ataxia; Molecular biology; Pathology; Cell biology; Mitochondrion; Internal medicine; Immunohistochemistry; Heart failure; Medicine; Immunology; Vimentin; Neuroscience","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001164498,0.0006422202,0.0003821831,0.0006298156,0.0004133143,0.0002274735,0.000157419,0.0003994718,0.002898533],"category_scores_gemma":[0.0002617487,0.0001133624,0.0001955494,0.0003675885,0.0003507678,0.0001912713,0.00029003,0.0002096885,0.000871051],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003699377,"about_ca_system_score_gemma":0.0002475983,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001116323,"about_ca_topic_score_gemma":0.001291921,"domain_scores_codex":[0.9999043,0.000009072209,0.00001002923,0.00003141918,0.00002354681,0.00002162679],"domain_scores_gemma":[0.9998945,0.00001289659,0.0000411444,0.000005354343,0.0000217743,0.00002435014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001024873,0.0002259073,0.09375998,0.001429733,0.0003057831,0.2935464,0.0007618011,0.000467844,0.4583497,0.005974142,0.02277362,0.1213802],"study_design_scores_gemma":[0.00009942093,0.000597588,0.3031426,0.0003391846,0.0002192499,0.5431208,0.0003559479,0.0008081449,0.04627265,0.003099837,0.1018921,0.00005244124],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9307349,0.01784856,0.006282946,0.00155982,0.0004098233,0.0001722022,0.002219839,0.0009756077,0.03979612],"genre_scores_gemma":[0.9810413,0.004088577,0.001123721,0.0005858608,0.0001341111,0.00003145071,0.001068101,0.00003814187,0.01188876],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002898533,"threshold_uncertainty_score":0.009696603,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03658505865980455,"score_gpt":0.2306884284722085,"score_spread":0.1941033698124039,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}