{"id":"W4200032934","doi":"10.1016/j.fochms.2021.100069","title":"Peptides GWN and GW protect kidney cells against Dasatinib induced mitochondrial injury in a SIRT1 dependent manner","year":2021,"lang":"en","type":"article","venue":"Food Chemistry Molecular Sciences","topic":"Sirtuins and Resveratrol in Medicine","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Dasatinib; Mitochondrion; Kidney; Chemistry; Cell biology; Cancer research; Biology; Tyrosine kinase; Endocrinology; Signal transduction","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002818797,0.0002285593,0.0003461447,0.00007328826,0.0001216543,0.00007827899,0.000191424,0.0001806395,0.00007339175],"category_scores_gemma":[0.0004639235,0.0001821893,0.00008077356,0.0004995432,0.000298596,0.00007011439,0.0001414563,0.0003963818,0.000003538195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004517836,"about_ca_system_score_gemma":0.0005996975,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001924118,"about_ca_topic_score_gemma":0.000003660503,"domain_scores_codex":[0.9978883,0.00005328136,0.000333098,0.000659647,0.0006726586,0.0003930578],"domain_scores_gemma":[0.9991093,0.00002765911,0.00009081201,0.0003321718,0.00009659018,0.0003435208],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005517114,0.0001162446,0.000478297,0.0001683435,0.00003392415,0.0004959274,0.0001498716,0.00001234728,0.9971101,0.00001063941,0.0002147716,0.001154416],"study_design_scores_gemma":[0.00168211,0.0004524964,0.0002931608,0.0003921539,0.00003591053,0.0001244674,0.000545316,0.0002059745,0.9954302,0.0000820198,0.0005439158,0.0002122163],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9924299,0.0005115732,0.00002842312,0.001801557,0.00023483,0.0003260954,0.00001093341,0.0000312107,0.004625505],"genre_scores_gemma":[0.9964858,0.00005722028,0.001604242,0.001172529,0.0002555125,0.00004785892,0.00001817257,0.00001649186,0.0003421705],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004283335,"threshold_uncertainty_score":0.7429462,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01365842405897993,"score_gpt":0.2655574219546487,"score_spread":0.2518989978956688,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}