{"id":"W4200050779","doi":"10.1016/j.ijrobp.2021.07.004","title":"Quality of Life Implications of Dose-Escalated External Beam Radiation for Localized Prostate Cancer: Results of a Prospective Randomized Phase 3 Clinical Trial, NRG/RTOG 0126","year":2021,"lang":"en","type":"article","venue":"International Journal of Radiation Oncology*Biology*Physics","topic":"Prostate Cancer Diagnosis and Treatment","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université du Québec à Montréal; Juravinski Cancer Centre; Alberta Cancer Foundation; Hamilton Health Sciences; Hôtel-Dieu de Québec; McGill University; Centre Hospitalier de l’Université de Montréal","funders":"National Center for Advancing Translational Sciences; National Cancer Institute; National Institutes of Health; AbbVie; Eisai; Varian Medical Systems; Elekta; AstraZeneca","keywords":"Medicine; Prostate cancer; External beam radiation; Randomized controlled trial; Quality (philosophy); Oncology; External beam radiotherapy; Quality of life (healthcare); Clinical trial; Radiation therapy; Medical physics; Cancer; Internal medicine; Nursing","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003110566,0.001490591,0.001676929,0.000398624,0.0004728508,0.001096656,0.0009923285,0.001465464,0.004553677],"category_scores_gemma":[0.002260725,0.0005220982,0.002664354,0.0005606036,0.00159391,0.000767473,0.0006160625,0.003374581,0.0005357688],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008133283,"about_ca_system_score_gemma":0.001225772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009680128,"about_ca_topic_score_gemma":0.001722174,"domain_scores_codex":[0.9981177,0.001337497,0.00006673608,0.0002039092,0.0001136595,0.0001605655],"domain_scores_gemma":[0.9984031,0.0004788565,0.0005150522,0.000159992,0.00005683897,0.0003861656],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9604515,0.01551323,0.001890015,0.0002209873,0.001032672,0.00002651758,0.00005773707,0.001337372,0.003496333,0.0000906542,0.0005013237,0.01538172],"study_design_scores_gemma":[0.7232124,0.2639418,0.009749694,0.00003061985,0.0008482232,0.00004107544,0.00004283608,0.0006223422,0.0008366163,0.0001896583,0.0004595871,0.00002508099],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960753,0.001053356,0.0003074565,0.0003203237,0.00009128582,0.0008158715,0.0005901186,0.00003323242,0.0007128665],"genre_scores_gemma":[0.9948086,0.0006058118,0.0009579533,0.0004498265,0.0001449629,0.00113905,0.0008686908,0.00002295674,0.001002248],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004553677,"threshold_uncertainty_score":0.01645046,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06844245345334565,"score_gpt":0.4590741424599416,"score_spread":0.390631689006596,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}