{"id":"W4200063333","doi":"10.1016/j.cellsig.2021.110222","title":"Apolipoprotein A-I carboxy-terminal domain residues 187–243 are required for adiponectin-induced cholesterol efflux","year":2021,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Adipokines, Inflammation, and Metabolic Diseases","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; McGill University Health Centre; Heart and Stroke Foundation of Canada","keywords":"ABCA1; Efflux; Cholesterol; Adiponectin; Chemistry; ATP Binding Cassette Transporter 1; Mutant; Apolipoprotein B; Baby hamster kidney cell; Biochemistry; Biology; Endocrinology; Transporter; Insulin resistance; Cell; Gene; Insulin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0004814588,0.0003723062,0.0006882894,0.0001791197,0.0002846431,0.00009460181,0.0001761833,0.0002194726,0.0001550439],"category_scores_gemma":[0.000509307,0.0003684714,0.0003611504,0.000292995,0.00006900987,0.0001726924,0.00005272798,0.0002274333,0.00004344812],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009227948,"about_ca_system_score_gemma":0.0004118027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006074526,"about_ca_topic_score_gemma":0.00006218017,"domain_scores_codex":[0.9974561,0.0001462811,0.0006550327,0.0006611513,0.0004784977,0.0006029842],"domain_scores_gemma":[0.9980744,0.0001509707,0.0003045884,0.00059709,0.0004790259,0.000393918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002790595,0.0002194321,0.002810229,0.000771399,0.0002419988,0.0003567193,0.0007176611,0.00005881925,0.9908342,0.0004276118,0.0002315051,0.003051311],"study_design_scores_gemma":[0.005409502,0.0002423332,0.006969525,0.001138728,0.0009205774,0.0001648056,0.0009652239,0.000629505,0.9595245,0.001010328,0.02240715,0.0006178319],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862513,0.002579125,0.00803936,0.0005127046,0.0004149027,0.00111335,0.00003821477,0.000185256,0.0008658004],"genre_scores_gemma":[0.9900741,0.0000511103,0.003716514,0.0004234361,0.002379721,0.0002448947,0.000376748,0.0001020238,0.002631481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03130976,"threshold_uncertainty_score":0.9998767,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02883675673008861,"score_gpt":0.2693070406258523,"score_spread":0.2404702838957636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}