{"id":"W4200063333","doi":"10.1016/j.cellsig.2021.110222","title":"Apolipoprotein A-I carboxy-terminal domain residues 187–243 are required for adiponectin-induced cholesterol efflux","year":2021,"lang":"en","type":"article","venue":"Cellular Signalling","topic":"Adipokines, Inflammation, and Metabolic Diseases","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; McGill University Health Centre; Heart and Stroke Foundation of Canada","keywords":"ABCA1; Efflux; Cholesterol; Adiponectin; Chemistry; ATP Binding Cassette Transporter 1; Mutant; Apolipoprotein B; Baby hamster kidney cell; Biochemistry; Biology; Endocrinology; Transporter; Insulin resistance; Cell; Gene; Insulin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001476907,0.0002478385,0.0002657852,0.0001196529,0.0002448336,0.0004996288,0.0001961778,0.000295102,0.002496718],"category_scores_gemma":[0.0002485925,0.0001907071,0.0003947139,0.0000958712,0.0002402451,0.0002251719,0.000196711,0.0004974796,0.00164781],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002424706,"about_ca_system_score_gemma":0.0002301885,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005412831,"about_ca_topic_score_gemma":0.0005163191,"domain_scores_codex":[0.9999001,0.00002064556,0.00001140978,0.00001816936,0.00002025653,0.00002932826],"domain_scores_gemma":[0.9997543,0.00004574388,0.00008530237,0.00002982812,0.00002584192,0.00005900327],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008173799,0.00004600724,0.001170579,0.00004564686,0.00002092895,0.000666566,0.00002536771,0.0001383481,0.9947798,0.0002698879,0.000188241,0.001831328],"study_design_scores_gemma":[0.0001809755,0.000265317,0.06228935,0.00003902562,0.00006326262,0.003014813,0.0001984714,0.002513283,0.9252236,0.000409634,0.00576971,0.00003249652],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9944851,0.001093342,0.002350397,0.0001417122,0.00005083005,0.00001650785,0.0004825356,0.00006148665,0.001318014],"genre_scores_gemma":[0.9956294,0.0003429152,0.001496237,0.00009242896,0.00001474238,0.00001554608,0.0008935059,0.00002307852,0.001492154],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002496718,"threshold_uncertainty_score":0.008352339,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02883675673008861,"score_gpt":0.2693070406258523,"score_spread":0.2404702838957636,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}