{"id":"W4200064655","doi":"10.3390/bioengineering8120220","title":"Is Culture Expansion Necessary in Autologous Mesenchymal Stromal Cell Therapy to Obtain Superior Results in the Management of Knee Osteoarthritis?—Meta-Analysis of Randomized Controlled Trials","year":2021,"lang":"en","type":"review","venue":"Bioengineering","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Research Foundation of Korea; National Research Foundation","keywords":"Mesenchymal stem cell; Osteoarthritis; Medicine; Randomized controlled trial; Meta-analysis; Physical therapy; Oncology; Surgery; Internal medicine; Alternative medicine; Pathology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.04684515,0.003632354,0.02557444,0.005258173,0.0007471175,0.00553805,0.002595552,0.003893563,0.003428659],"category_scores_gemma":[0.07281186,0.002006324,0.0696242,0.005675508,0.001316437,0.003380395,0.001795953,0.003196797,0.0003558685],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002345899,"about_ca_system_score_gemma":0.002236195,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002529562,"about_ca_topic_score_gemma":0.003887627,"domain_scores_codex":[0.944267,0.0359177,0.01202245,0.003787398,0.003284553,0.0007209714],"domain_scores_gemma":[0.9420739,0.04438281,0.008857729,0.002670291,0.001567529,0.0004476852],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.005744242,0.0000363564,0.003295867,0.0784685,0.9050305,0.00005383566,0.0000369817,0.0004239691,0.0002339617,0.0001038039,0.0002363566,0.00633561],"study_design_scores_gemma":[0.002186589,0.0004376293,0.002213295,0.005364008,0.9884833,0.00004817339,0.00002476117,0.0002472871,0.0001409142,0.0002339593,0.0006022926,0.00001789008],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01180204,0.9823213,0.002680349,0.0006135725,0.0007556824,0.0008385975,0.0004576631,0.00007107138,0.00045972],"genre_scores_gemma":[0.61277,0.3630426,0.01148713,0.003819218,0.001576722,0.005070554,0.001429391,0.0001680106,0.0006364519],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.04684515,"threshold_uncertainty_score":0.2477438,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1300668715437402,"score_gpt":0.3904986671019924,"score_spread":0.2604317955582521,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}