{"id":"W4200071588","doi":"10.1016/j.adro.2021.100859","title":"Association of Pretreatment Hippocampal Volume With Neurocognitive Function in Patients Treated With Hippocampal Avoidance Whole Brain Radiation Therapy for Brain Metastases: Secondary Analysis of NRG Oncology/RTOG 0933","year":2021,"lang":"en","type":"article","venue":"Advances in Radiation Oncology","topic":"Brain Metastases and Treatment","field":"Medicine","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; Saskatchewan Cancer Agency","funders":"National Cancer Institute; NRG Oncology; Avid Radiopharmaceuticals; National Institute on Aging; Astellas Pharma; Elekta; Celgene; Biogen; Roche; Merck; Pfizer; Eli Lilly and Company","keywords":"Medicine; Neurocognitive; Verbal learning; Radiation therapy; Hippocampal formation; Nuclear medicine; Internal medicine; Cognition; Psychiatry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003471518,0.000250068,0.0002985143,0.000350215,0.0001468735,0.0002766639,0.0002475907,0.0001975605,0.000970546],"category_scores_gemma":[0.0009274335,0.00009888456,0.0004422161,0.0003314163,0.0001345191,0.0001577199,0.0002093481,0.0003999017,0.0001707518],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003143343,"about_ca_system_score_gemma":0.0003029197,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002574951,"about_ca_topic_score_gemma":0.00360706,"domain_scores_codex":[0.999843,0.00003884522,0.0000164711,0.00003416828,0.00003845528,0.00002896397],"domain_scores_gemma":[0.9993992,0.0001141789,0.0002571124,0.00005624005,0.0000684212,0.0001048854],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00175468,0.00007930873,0.9946787,0.00001661881,0.0001139213,0.00006064689,0.00002555289,0.0001091661,0.0009205705,0.00000627308,0.0001455824,0.002088999],"study_design_scores_gemma":[0.00004545188,0.0007525779,0.9983984,0.000002419844,0.00004493152,0.0001882208,0.00002163013,0.0002116007,0.0002220932,0.000006747577,0.000103939,0.000002105413],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.999598,0.000065608,0.00002025978,0.000008719914,0.000001246703,0.000007500487,0.0001821772,0.000002039335,0.000114544],"genre_scores_gemma":[0.9995813,0.00001375531,0.00001970089,0.000008970937,0.000003096473,0.000006687113,0.0003176504,0.000001048136,0.00004780758],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002574951,"threshold_uncertainty_score":0.005119979,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008041633150340927,"score_gpt":0.2965172129193429,"score_spread":0.288475579769002,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}