{"id":"W4200083348","doi":"10.1158/1541-7786.mcr-20-0527","title":"Syntaxin4-Munc18c Interaction Promotes Breast Tumor Invasion and Metastasis by Regulating MT1-MMP Trafficking","year":2021,"lang":"en","type":"article","venue":"Molecular Cancer Research","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia; BC Cancer Agency; University of Guelph","funders":"Government of Canada; Canadian Institutes of Health Research; Cancer Research Society; University of Guelph","keywords":"Metastasis; Breast tumor; Tumor cells; Breast cancer; Human breast; Cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001310027,0.0002507733,0.0001874448,0.000158709,0.0002684501,0.0002716214,0.0002231396,0.0003506093,0.001266102],"category_scores_gemma":[0.0001074687,0.0001058024,0.0001471791,0.00009337129,0.0002789997,0.0001650085,0.0001836618,0.0004410324,0.0002720742],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007052462,"about_ca_system_score_gemma":0.0003775974,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001027917,"about_ca_topic_score_gemma":0.001457502,"domain_scores_codex":[0.9998864,0.00002152107,0.00001041878,0.00001826044,0.00003084315,0.00003257009],"domain_scores_gemma":[0.9999171,0.000008159096,0.00003146573,0.000005874938,0.00001013451,0.00002716987],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001801566,0.00002578216,0.0002380408,0.00002559543,0.000006063306,0.00004819922,0.000005986908,0.00007513789,0.998697,0.000124666,0.00005882598,0.0005145596],"study_design_scores_gemma":[0.0000371273,0.0001744965,0.006698738,0.000005341818,0.00002179891,0.0002707463,0.00002728824,0.001822508,0.988042,0.00006328119,0.002832112,0.000004539178],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9962793,0.001153389,0.001155429,0.000277422,0.00002922289,0.00001899043,0.000159168,0.00007288878,0.0008542053],"genre_scores_gemma":[0.9965861,0.0005138674,0.0009666337,0.00006772413,0.000009291359,0.00001979649,0.0001866429,0.00001314957,0.001636706],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001266102,"threshold_uncertainty_score":0.00511694,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03201412088272646,"score_gpt":0.3234851978439381,"score_spread":0.2914710769612117,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}