{"id":"W4200086368","doi":"10.1016/j.redox.2021.102225","title":"Mitochondria in human neutrophils mediate killing of Staphylococcus aureus","year":2021,"lang":"en","type":"article","venue":"Redox Biology","topic":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","field":"Immunology and Microbiology","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; Queen's University","funders":"National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research","keywords":"Mitochondrion; Staphylococcus aureus; Microbiology; NADPH oxidase; Apocynin; Biology; Mitochondrial ROS; Innate immune system; Reactive oxygen species; Cell biology; Antimycin A; Chemistry; Bacteria; Immune system; Immunology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002087456,0.0002462291,0.0006345399,0.0002378005,0.00009625407,0.000005613155,0.0002908541,0.0004520263,0.0007440227],"category_scores_gemma":[0.0000785853,0.000220938,0.0001426262,0.0003362661,0.0002792152,0.0000527502,0.0001744685,0.0004146686,0.0001329974],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000040012,"about_ca_system_score_gemma":0.00009960774,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008839121,"about_ca_topic_score_gemma":0.0001079402,"domain_scores_codex":[0.997789,0.0005349389,0.0005803921,0.0005317125,0.00002892549,0.0005350891],"domain_scores_gemma":[0.9990223,0.0001607506,0.0001953899,0.0004500822,0.0001379485,0.00003355279],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005569245,0.0001442229,0.002115644,0.00001920502,0.0001022541,0.00006786402,0.0001803168,0.000007113098,0.9789124,0.01709726,0.000179409,0.001118668],"study_design_scores_gemma":[0.001495478,0.0002974288,0.002448558,0.00004686217,0.00002483363,0.00002065514,0.0001870759,0.000001215634,0.9782499,0.005536694,0.01146275,0.0002285315],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921939,0.005140767,0.000241423,0.0003150351,0.0009855116,0.00020355,0.00007879375,0.00004335776,0.0007976481],"genre_scores_gemma":[0.9980529,0.0004118132,0.0003294994,0.0002167791,0.00008994518,0.00002910886,0.0003377021,0.00002315185,0.0005091227],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01156057,"threshold_uncertainty_score":0.9009591,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01399817571108339,"score_gpt":0.2640517917421423,"score_spread":0.2500536160310589,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}