{"id":"W4200095907","doi":"10.1200/jco.21.00941","title":"Health-Related Quality of Life in Metastatic, Hormone-Sensitive Prostate Cancer: ENZAMET (ANZUP 1304), an International, Randomized Phase III Trial Led by ANZUP","year":2021,"lang":"en","type":"article","venue":"Journal of Clinical Oncology","topic":"Prostate Cancer Treatment and Research","field":"Medicine","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Kingston Health Sciences Centre; University of Ottawa; Alberta Cancer Foundation; BC Cancer Agency","funders":"National Health and Medical Research Council; Australian and New Zealand Urogenital and Prostate Cancer Trials Group; Astellas Pharma","keywords":"Medicine; Enzalutamide; Quality of life (healthcare); Prostate cancer; Internal medicine; Discontinuation; Randomized controlled trial; Cancer; Oncology; Physical therapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001382753,0.0008884701,0.001467796,0.0003601383,0.0002381004,0.000526297,0.0006802143,0.0007428306,0.003113139],"category_scores_gemma":[0.001176985,0.0002721035,0.0008670068,0.0003472316,0.0005515797,0.0004688576,0.000338275,0.001722996,0.0003264635],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005555858,"about_ca_system_score_gemma":0.0007972502,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001066142,"about_ca_topic_score_gemma":0.003835623,"domain_scores_codex":[0.9993326,0.0004871665,0.00001984375,0.00006175314,0.00005065732,0.00004790219],"domain_scores_gemma":[0.9996746,0.00007537875,0.00009706814,0.00002197112,0.00002531577,0.0001056901],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.8024933,0.01453342,0.005581944,0.001794543,0.001921702,0.00009399219,0.0001067841,0.002010051,0.01018598,0.0003751831,0.003936194,0.1569669],"study_design_scores_gemma":[0.8423793,0.1348476,0.01623199,0.0001155186,0.000860423,0.0001813695,0.00004225722,0.00139385,0.0008686555,0.0002845234,0.002761175,0.00003334619],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9846578,0.008384941,0.0005381313,0.0007304006,0.0001266145,0.002146212,0.001022405,0.0001145233,0.002278998],"genre_scores_gemma":[0.9842547,0.003554689,0.00262696,0.001212081,0.0001502188,0.004160414,0.001470784,0.00002243918,0.002547808],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003113139,"threshold_uncertainty_score":0.01041454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2063521967947266,"score_gpt":0.5675658819912144,"score_spread":0.3612136851964878,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}