{"id":"W4200101369","doi":"10.3390/immuno2010002","title":"Macrophages and Epithelial Cells Mutually Interact through NLRP3 to Clear Infection and Enhance the Gastrointestinal Barrier","year":2021,"lang":"en","type":"article","venue":"Immuno","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Inflammasome; Citrobacter rodentium; Secretion; Proinflammatory cytokine; Barrier function; Cell biology; Interleukin 22; Macrophage; Microbiology; Biology; Cytokine; Pathogen; Tight junction; Epithelium; Inflammation; Immunology; Chemistry; Interleukin; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002104979,0.0001376991,0.0001520388,0.00003373418,0.0002779787,0.0000665703,0.00007833355,0.0000704468,0.0003738582],"category_scores_gemma":[0.0001523877,0.0001054985,0.00004370354,0.00008699107,0.0001442746,0.000182336,0.0001517074,0.0002586128,0.0004039851],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002907058,"about_ca_system_score_gemma":0.00004617864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001918532,"about_ca_topic_score_gemma":0.00003348722,"domain_scores_codex":[0.9990391,0.0002748533,0.0002179231,0.0002171662,0.00002781055,0.0002231993],"domain_scores_gemma":[0.9994476,0.0001597279,0.00006720602,0.000225676,0.00008687336,0.00001295017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000400789,0.00001998016,0.0001929198,0.00001007438,0.0000355544,0.00001105207,0.001315316,0.000002156204,0.9894321,0.0002702174,0.0003188023,0.007991018],"study_design_scores_gemma":[0.0003897872,0.0002961282,0.02143919,0.00006828847,0.00002176592,0.000714455,0.0004479221,0.000002791824,0.9153957,0.00008205906,0.06102315,0.0001187982],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9946601,0.002577948,0.000718157,0.0007087227,0.0004826048,0.0001442052,0.00001030917,0.00003278609,0.0006651395],"genre_scores_gemma":[0.9951139,0.0005125056,0.000270723,0.0003853931,0.0000441399,0.00001390259,0.00001685388,0.00001338139,0.003629189],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07403646,"threshold_uncertainty_score":0.5192547,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005863396384165631,"score_gpt":0.2438945526358242,"score_spread":0.2380311562516585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}