{"id":"W4200101369","doi":"10.3390/immuno2010002","title":"Macrophages and Epithelial Cells Mutually Interact through NLRP3 to Clear Infection and Enhance the Gastrointestinal Barrier","year":2021,"lang":"en","type":"article","venue":"Immuno","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Inflammasome; Citrobacter rodentium; Secretion; Proinflammatory cytokine; Barrier function; Cell biology; Interleukin 22; Macrophage; Microbiology; Biology; Cytokine; Pathogen; Tight junction; Epithelium; Inflammation; Immunology; Chemistry; Interleukin; In vitro","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003801117,0.0005177961,0.0004048138,0.0002577989,0.0002021237,0.0004925999,0.0002264605,0.0006982011,0.001199743],"category_scores_gemma":[0.0002312168,0.0001946436,0.0004130026,0.0001539635,0.0004027917,0.0005723428,0.0008929303,0.0006998279,0.0005739981],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002349594,"about_ca_system_score_gemma":0.0002858701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001936403,"about_ca_topic_score_gemma":0.0002681015,"domain_scores_codex":[0.9994136,0.0002029927,0.00004611509,0.00008110966,0.0001277283,0.0001284281],"domain_scores_gemma":[0.9998243,0.0000212,0.00006176344,0.00002512018,0.00003048413,0.00003707116],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002344553,0.00005828818,0.0006611521,0.0001705741,0.00001767523,0.0003182519,0.00004012779,0.00006348803,0.9942321,0.0003296168,0.0001032739,0.003771042],"study_design_scores_gemma":[0.00009269956,0.001527493,0.01986544,0.00009107537,0.00007125242,0.002169584,0.0002775824,0.001936797,0.9555029,0.00100267,0.01744119,0.00002118888],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9311126,0.02877807,0.03143046,0.001394296,0.0002187464,0.0001681345,0.0002789449,0.0003299947,0.006288655],"genre_scores_gemma":[0.9825932,0.003665818,0.009351567,0.0004302469,0.00005375018,0.0001151861,0.0001473177,0.00001939248,0.003623552],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001199743,"threshold_uncertainty_score":0.004013598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005863396384165631,"score_gpt":0.2438945526358242,"score_spread":0.2380311562516585,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}