{"id":"W4200107345","doi":"10.1080/07853890.2021.2014557","title":"Gut permeability and osteoarthritis, towards a mechanistic understanding of the pathogenesis: a systematic review","year":2021,"lang":"en","type":"review","venue":"Annals of Medicine","topic":"Inflammatory mediators and NSAID effects","field":"Medicine","cited_by":56,"is_retracted":false,"has_abstract":true,"ca_institutions":"Surgical Specialties (Canada)","funders":"","keywords":"Pathogenesis; Osteoarthritis; Dysbiosis; Gut flora; Inflammation; Intestinal permeability; Phenotype; Immune system; Immunology; Medicine; Microbiome; Tight junction; Bioinformatics; Biology; Pathology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003472537,0.0004571496,0.006789656,0.0001504855,0.00006336845,0.000003984,0.0002195713,0.0002582742,0.00009672817],"category_scores_gemma":[0.006077986,0.0002390981,0.0007339065,0.0005473311,0.0004432076,0.00002643678,0.0001318173,0.0003414151,0.000001984384],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006826605,"about_ca_system_score_gemma":0.0006470967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001297684,"about_ca_topic_score_gemma":0.000004536715,"domain_scores_codex":[0.9955951,0.00102484,0.001839058,0.0004025942,0.0008537887,0.0002846109],"domain_scores_gemma":[0.9965258,0.0006166227,0.001245904,0.001038693,0.0003671394,0.0002058356],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"systematic_review","study_design_gemma":"systematic_review","study_design_scores_codex":[0.000006857093,0.00003484449,0.000002163971,0.9593176,0.0002829104,0.0000670755,0.0001025589,4.075857e-9,0.00001442775,0.0008133268,0.0005874931,0.0387708],"study_design_scores_gemma":[0.000482518,0.0004912949,0.000009775216,0.9763573,0.00977273,0.0005290949,0.0001733561,0.00000119101,0.00001059663,0.0001216837,0.01187935,0.0001711056],"study_design_candidate":"systematic_review","study_design_consensus":"systematic_review","genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00003170324,0.9946582,0.00002483273,0.0008590219,0.0003270271,0.00382057,0.00004954195,0.00001480479,0.0002143506],"genre_scores_gemma":[0.0009097054,0.9979101,0.00001377075,0.0006563898,0.0001783391,0.0001734204,0.00003789587,0.00004515916,0.00007516731],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.03859969,"threshold_uncertainty_score":0.9750138,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1547811990651589,"score_gpt":0.3830127004910419,"score_spread":0.228231501425883,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}