{"id":"W4200113470","doi":"10.1101/2021.12.13.472149","title":"Oxoglutarate dehydrogenase coordinates myofibril growth by maintaining amino acid homeostasis","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Cardiomyopathy and Myosin Studies","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Dalhousie University","funders":"Canadian Institutes of Health Research","keywords":"Myofibril; Sarcomere; Myosin; Actin; Cell biology; Protein subunit; Biology; Biochemistry; Chemistry; Biophysics; Myocyte","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001183311,0.0002781654,0.0001701764,0.00025291,0.0001494336,0.0002842948,0.0002205262,0.0002880547,0.001601926],"category_scores_gemma":[0.0000789365,0.0001192068,0.0001162217,0.0001377867,0.0002322413,0.0001758634,0.0002750168,0.0003276899,0.0008332617],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002562433,"about_ca_system_score_gemma":0.0001397356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005741023,"about_ca_topic_score_gemma":0.0007820938,"domain_scores_codex":[0.9999336,0.000007449872,0.000005448676,0.00001982285,0.00001594685,0.00001770271],"domain_scores_gemma":[0.9999337,0.000006770726,0.00001769082,0.00001163162,0.00001041637,0.00001982136],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003297395,0.000004676356,0.0002188011,0.00001288738,0.000001356827,0.00004036802,0.000006092218,0.00002857001,0.9990496,0.0001246687,0.0000532744,0.0004267182],"study_design_scores_gemma":[0.00001857218,0.00005172743,0.01016915,0.0000071758,0.0000069889,0.0002154272,0.0000393522,0.002095706,0.9840055,0.0002224669,0.003163351,0.000004567611],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9802215,0.001389493,0.01361684,0.0003281131,0.0000658647,0.00002084279,0.001040149,0.0003254349,0.002991717],"genre_scores_gemma":[0.9872968,0.0005184171,0.004940522,0.00005709905,0.00001540579,0.00001377349,0.0008410689,0.000099927,0.006216845],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001601926,"threshold_uncertainty_score":0.005358994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01217557565822696,"score_gpt":0.2233855116084699,"score_spread":0.211209935950243,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}