{"id":"W4200125680","doi":"10.1016/j.radonc.2021.12.029","title":"Identifying optimal clinical trial candidates for locoregionally advanced nasopharyngeal carcinoma: Analysis of 9468 real-world cases and validation by two phase 3 multicentre, randomised controlled trial","year":2021,"lang":"en","type":"article","venue":"Radiotherapy and Oncology","topic":"Head and Neck Cancer Studies","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre","funders":"","keywords":"Nasopharyngeal carcinoma; Medicine; Internal medicine; Hazard ratio; Oncology; Confidence interval; Clinical trial; Risk stratification; Stage (stratigraphy); Receiver operating characteristic; Randomized controlled trial; Radiation therapy; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02999063,0.001463737,0.005918322,0.0006140571,0.0007335243,0.002628318,0.001167011,0.002484676,0.004306017],"category_scores_gemma":[0.04051055,0.0008998339,0.004939678,0.001114456,0.002300189,0.002940333,0.001055648,0.002422378,0.0006209163],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008684136,"about_ca_system_score_gemma":0.001087717,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000343344,"about_ca_topic_score_gemma":0.0008497228,"domain_scores_codex":[0.9722598,0.0223933,0.001944497,0.001933227,0.0008313192,0.0006378472],"domain_scores_gemma":[0.9601789,0.03024522,0.005684375,0.002233331,0.0007919794,0.0008661361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.9131488,0.001479637,0.02995645,0.00397016,0.01756487,0.0001607263,0.0003956378,0.001885976,0.002661425,0.0004854739,0.001073441,0.02721756],"study_design_scores_gemma":[0.7751572,0.07625467,0.08401341,0.001021693,0.04460707,0.0004034732,0.0005617278,0.005087122,0.002128533,0.003377204,0.007176719,0.0002112371],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9501044,0.03846378,0.004692311,0.0007771975,0.0002745468,0.003737515,0.0009222528,0.00005936212,0.0009686904],"genre_scores_gemma":[0.9925635,0.001673467,0.002548815,0.0003817347,0.00008967815,0.001569733,0.0008806569,0.00002705943,0.0002652916],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02999063,"threshold_uncertainty_score":0.1586075,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06566082748412855,"score_gpt":0.4462479820436401,"score_spread":0.3805871545595116,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}