{"id":"W4200132345","doi":"10.1128/spectrum.01584-21","title":"Cell-Penetrating Antimicrobial Peptides Derived from an Atypical Staphylococcal δ-Toxin","year":2021,"lang":"en","type":"article","venue":"Microbiology Spectrum","topic":"Antimicrobial Peptides and Activities","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Natural Sciences and Engineering Research Council of Canada; Government of Canada; Ministry of Agriculture - Saskatchewan","keywords":"Virulence; Antimicrobial peptides; Antimicrobial; Microbiology; Toxin; Virulence factor; Staphylococcus aureus; Biology; Antibiotic resistance; Bacteria; Cell; Antibiotics; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001867312,0.0005859751,0.0008126443,0.0001301543,0.0006056135,0.0001112154,0.0005265394,0.0008290691,0.003339653],"category_scores_gemma":[0.00004910741,0.0005823654,0.000329126,0.0002144957,0.0008263757,0.0002717387,0.0003694212,0.0009346737,0.001408963],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00009099929,"about_ca_system_score_gemma":0.0002635775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004579502,"about_ca_topic_score_gemma":0.0007691665,"domain_scores_codex":[0.9962883,0.0006323595,0.0006657989,0.001199895,0.00002902213,0.00118462],"domain_scores_gemma":[0.9986356,0.0002375897,0.0002470216,0.0006993087,0.00009345424,0.00008705653],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002974466,0.000479664,0.005910266,0.00001639091,0.0002040067,0.0001095867,0.0003857434,0.00001366984,0.9809659,0.0002974968,0.01105207,0.0002678382],"study_design_scores_gemma":[0.001790924,0.0002438471,0.008464527,0.00004740785,0.00008298808,0.0004356003,0.0007338063,0.00000521292,0.9769254,0.0002658792,0.01029422,0.0007102341],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9930441,0.00150642,0.0005607094,0.001217101,0.001433176,0.0002386496,0.0007357182,0.0002593891,0.001004776],"genre_scores_gemma":[0.9903185,0.0001080371,0.002059727,0.001917302,0.0003390102,0.00001079739,0.003079297,0.00007299796,0.002094298],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004040469,"threshold_uncertainty_score":0.9996628,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01010935801061057,"score_gpt":0.2242320356155835,"score_spread":0.2141226776049729,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}