{"id":"W4200167549","doi":"10.1016/j.ydbio.2021.12.014","title":"Cdx regulates gene expression through PRC2-mediated epigenetic mechanisms","year":2021,"lang":"en","type":"article","venue":"Developmental Biology","topic":"Birth, Development, and Health","field":"Medicine","cited_by":3,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research","keywords":"Biology; Endoderm; Yolk sac; Mesoderm; Epigenetics; Cell biology; Genetics; Embryonic stem cell; Regulation of gene expression; Gene expression; Gene; Ectoderm; Embryo","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001964806,0.0002786759,0.0004894724,0.00009029343,0.0002075218,0.00001396475,0.0001236448,0.0003559901,0.001106327],"category_scores_gemma":[0.0001244315,0.0002363866,0.00007220457,0.0003154077,0.0001086653,0.0000603247,0.000190657,0.0002371661,0.0004799263],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002160386,"about_ca_system_score_gemma":0.001004811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002201874,"about_ca_topic_score_gemma":0.00002983642,"domain_scores_codex":[0.9979272,0.0001110707,0.0005292624,0.0006331706,0.0001899332,0.0006092916],"domain_scores_gemma":[0.9991841,0.00006890575,0.0001216285,0.0002436315,0.0001516569,0.0002300972],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008486104,0.000153626,0.01275124,0.00006712311,0.00008147091,0.0001524711,0.0008746402,1.619686e-7,0.9741895,0.008524737,0.001454917,0.001665238],"study_design_scores_gemma":[0.001518087,0.0001539669,0.04246059,0.0001020322,0.00001610405,0.0004767693,0.0004165762,0.000005413038,0.9203703,0.02405977,0.01011483,0.000305546],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804397,0.001832258,0.003830836,0.002441893,0.001047768,0.0006049732,0.00004296144,0.0002501799,0.009509454],"genre_scores_gemma":[0.7332698,0.02027944,0.2373886,0.006384716,0.0001344424,0.00007394858,0.001942538,0.00005017443,0.0004763992],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2471699,"threshold_uncertainty_score":0.9998068,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02864704226192427,"score_gpt":0.2899382220802616,"score_spread":0.2612911798183373,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}