{"id":"W4200173896","doi":"10.3390/cimb44010006","title":"Gigantol Improves Cholesterol Metabolism and Progesterone Biosynthesis in MA-10 Leydig Cells","year":2021,"lang":"en","type":"review","venue":"Current Issues in Molecular Biology","topic":"Biological and pharmacological studies of plants","field":"Medicine","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Moncton","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Biosynthesis; Steroid biosynthesis; Ferulic acid; Internal medicine; Endocrinology; Chemistry; Cholesterol side-chain cleavage enzyme; Testosterone (patch); Steroid; Leydig cell; Metabolism; Biology; Biochemistry; Gene; Cytochrome P450; Hormone; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001573687,0.0004435283,0.0005856627,0.0009603681,0.000138923,0.0003759115,0.0003668441,0.0003645264,0.002101456],"category_scores_gemma":[0.0001227499,0.0001120755,0.0003156346,0.0004758559,0.0001603592,0.0003438257,0.0002357419,0.0006911083,0.0006456034],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002895189,"about_ca_system_score_gemma":0.0003025627,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007364984,"about_ca_topic_score_gemma":0.001808978,"domain_scores_codex":[0.9999492,0.000008237347,0.000006376124,0.000009670182,0.00001809803,0.000008490079],"domain_scores_gemma":[0.9999615,0.00001023363,0.000008948174,0.00000170765,0.00001075841,0.000006858245],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006268359,0.0002340839,0.0004920699,0.02341431,0.0002190646,0.0005650087,0.0001022702,0.0003841485,0.09130367,0.002445662,0.01276409,0.8674488],"study_design_scores_gemma":[0.0001698578,0.001180656,0.009051687,0.001761002,0.0005006643,0.002574231,0.00009060419,0.0002899077,0.03755939,0.0012008,0.9455768,0.00004441628],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.005589038,0.9904088,0.0003879509,0.0003098153,0.0001539322,0.00001816608,0.0001260017,0.0000482243,0.002958036],"genre_scores_gemma":[0.03265193,0.96237,0.0007284568,0.0004164976,0.000108351,0.00001983986,0.0002960782,0.00001131511,0.003397531],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002101456,"threshold_uncertainty_score":0.00703007,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0666245408531086,"score_gpt":0.4134473356786147,"score_spread":0.3468227948255061,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}