{"id":"W4200180513","doi":"10.1016/j.eururo.2021.12.005","title":"International Bladder Cancer Group Consensus Statement on Clinical Trial Design for Patients with Bacillus Calmette-Guérin–exposed High-risk Non–muscle-invasive Bladder Cancer","year":2021,"lang":"en","type":"review","venue":"European Urology","topic":"Bladder and Urothelial Cancer Treatments","field":"Medicine","cited_by":89,"is_retracted":false,"has_abstract":false,"ca_institutions":"North York General Hospital; University of British Columbia; McGill University","funders":"","keywords":"Medicine; Bladder cancer; Clinical trial; Clinical endpoint; Internal medicine; Randomized controlled trial; Carcinoma in situ; Randomization; Clinical study design; Oncology; Gemcitabine; Cohort; Cancer; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.1238962,0.001795112,0.008030521,0.00163199,0.001200002,0.003762739,0.003950503,0.006877893,0.00970054],"category_scores_gemma":[0.143455,0.001189419,0.01091091,0.001954202,0.001602551,0.001660923,0.001618087,0.00658385,0.003221942],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002527533,"about_ca_system_score_gemma":0.01228495,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001970358,"about_ca_topic_score_gemma":0.004692607,"domain_scores_codex":[0.9043496,0.07526949,0.01326145,0.002109211,0.003954231,0.001056094],"domain_scores_gemma":[0.9152678,0.06213139,0.00825399,0.004168178,0.008385235,0.001793486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.03688542,0.000560853,0.00230854,0.2606897,0.01944602,0.0002178303,0.0006125736,0.001641319,0.002297112,0.01402519,0.1796097,0.4817056],"study_design_scores_gemma":[0.0977485,0.004258548,0.009520543,0.2421599,0.04403592,0.0004405,0.0003178824,0.002277453,0.002043145,0.03080055,0.5661155,0.0002815243],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.006112949,0.665454,0.05366476,0.04934702,0.02852999,0.1542443,0.01515495,0.001025161,0.02646678],"genre_scores_gemma":[0.05554976,0.2757333,0.2346683,0.05274877,0.007226406,0.3469608,0.01114511,0.0006757714,0.01529182],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.1238962,"threshold_uncertainty_score":0.6552333,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1139972207078701,"score_gpt":0.3872158354096365,"score_spread":0.2732186147017664,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}