{"id":"W4200181375","doi":"10.1101/2021.12.22.473822","title":"Transcriptome features of trained immunity in <i>Drosophila</i>","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Immune responses and vaccinations","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Institute of Genetics; Japan Society for the Promotion of Science","keywords":"Biology; Immunity; Immune system; Innate immune system; Acquired immune system; Drosophila melanogaster; Transcriptome; RNA interference; Gene; Epigenetics; Genetics; Gene expression; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006543132,0.0004931501,0.0009321079,0.000472751,0.0001422772,0.00005703012,0.0006853532,0.00104405,0.0002197015],"category_scores_gemma":[0.0002844734,0.0005358972,0.0003455979,0.0006134211,0.0001761519,0.0001189705,0.0003223645,0.001594647,0.00002258854],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000145721,"about_ca_system_score_gemma":0.0007230864,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003759438,"about_ca_topic_score_gemma":0.00002291748,"domain_scores_codex":[0.997327,0.00062416,0.0007668492,0.000641082,0.0000873441,0.0005535095],"domain_scores_gemma":[0.9978061,0.0001605134,0.0003661633,0.001228745,0.0003943097,0.00004414998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001620951,0.0004218329,0.001073454,0.0002362301,0.000278023,0.00002954958,0.00009446491,0.00001633773,0.9964839,0.001046243,0.0001537683,0.000004076153],"study_design_scores_gemma":[0.001347465,0.00005611019,0.3830199,0.0003797336,0.00009218657,9.934455e-8,0.00002888452,0.000002073348,0.6125998,0.000002246652,0.002034851,0.0004365538],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9773057,0.01971909,0.00007472278,0.0003726562,0.00147792,0.0005193118,0.0003655792,0.0001334938,0.00003153852],"genre_scores_gemma":[0.9983727,0.0008978039,0.0003470239,0.0001024849,0.0000451971,0.0001135769,0.000004744557,0.00007495876,0.00004145071],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3838841,"threshold_uncertainty_score":0.9997092,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01274052042957981,"score_gpt":0.2277877840438048,"score_spread":0.2150472636142249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}