{"id":"W4200187845","doi":"10.1371/journal.pntd.0010076","title":"Genetic diversity of Leptospira isolates in Lao PDR and genome analysis of an outbreak strain","year":2021,"lang":"en","type":"article","venue":"PLoS neglected tropical diseases","topic":"Leptospirosis research and findings","field":"Immunology and Microbiology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institut National de la Recherche Scientifique","funders":"Fonds de Recherche du Québec - Santé; Wellcome; Institut Pasteur; Canadian Network for Research and Innovation in Machining Technology, Natural Sciences and Engineering Research Council of Canada; Natural Sciences and Engineering Research Council of Canada; Wellcome Trust","keywords":"Leptospira; Biology; Outbreak; Genotype; Genetic diversity; Leptospira interrogans; Molecular epidemiology; Genome; Virulence; Multilocus sequence typing; Typing; Serotype; Genetics; Virology; Gene; Population; Medicine; Environmental health","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000004947023,0.0001240374,0.0004760433,0.0002803784,0.0000851088,0.00001107211,0.0001753497,0.0001365891,0.0008955871],"category_scores_gemma":[0.0002522179,0.0001150465,0.0001348558,0.0007538474,0.0003622125,0.00008381261,0.0002772993,0.0001611407,0.000005349137],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002369633,"about_ca_system_score_gemma":0.00006416063,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002613888,"about_ca_topic_score_gemma":0.0003766762,"domain_scores_codex":[0.9988076,0.0002329355,0.000279459,0.0003165435,0.00006785475,0.0002956218],"domain_scores_gemma":[0.9993556,0.0001334979,0.00007905153,0.000223619,0.000122425,0.00008584302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001021725,0.0005868776,0.5111204,0.00003291795,0.000675454,0.00001235312,0.0001662268,0.000009536651,0.4869322,0.00004124221,0.000002848165,0.0003177637],"study_design_scores_gemma":[0.0008643956,0.0002650954,0.9898574,0.00001694028,0.0006224017,0.000001020261,0.0001225783,0.00008218735,0.00792807,0.0001194848,0.00001274798,0.0001076744],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969531,0.002045059,0.00002849838,0.00003972801,0.0000124414,0.0001098359,0.0007589965,0.00001887394,0.00003343704],"genre_scores_gemma":[0.9993756,0.0001692139,0.0000696709,0.00003074728,0.000006431781,0.000005854922,0.0002917107,0.000006822082,0.00004399633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4790041,"threshold_uncertainty_score":0.980605,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01330465536916063,"score_gpt":0.2309519390157879,"score_spread":0.2176472836466273,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}