{"id":"W4200189057","doi":"10.3390/curroncol29010004","title":"New Strategies and Combinations to Improve Outcomes in Immunotherapy in Metastatic Non-Small-Cell Lung Cancer","year":2021,"lang":"en","type":"review","venue":"Current Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Princess Margaret Cancer Centre; University Health Network","funders":"","keywords":"Immunotherapy; Medicine; Lung cancer; Immune system; Tumor microenvironment; Cancer immunotherapy; Immune checkpoint; T cell; Clinical trial; Cancer; Immunology; Cancer research; Oncology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007412974,0.0006882495,0.001112541,0.001741386,0.000198367,0.0008296327,0.0007672851,0.0008104147,0.00299039],"category_scores_gemma":[0.0006293671,0.0002146594,0.0006672442,0.001115243,0.0003975601,0.001249976,0.000628089,0.002296069,0.001246827],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004376245,"about_ca_system_score_gemma":0.0005635673,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003883892,"about_ca_topic_score_gemma":0.001194779,"domain_scores_codex":[0.9997965,0.00005139477,0.00002866311,0.00002771117,0.00007474914,0.00002117595],"domain_scores_gemma":[0.9998114,0.0001040064,0.00002691561,0.000006110298,0.00003817392,0.00001351588],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00008850615,0.0001138763,0.0001332773,0.01426695,0.0001196835,0.0001600634,0.00005000426,0.0004630821,0.002250645,0.004894869,0.01513452,0.9623246],"study_design_scores_gemma":[0.00006082193,0.0003678584,0.000873689,0.004741163,0.0001718906,0.00150893,0.0000545713,0.000189326,0.0009667508,0.003107242,0.9879346,0.00002311527],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001753862,0.9983788,0.0001838716,0.000253454,0.0001702738,0.00001058318,0.00001419609,0.00000681624,0.000806662],"genre_scores_gemma":[0.001009171,0.9977574,0.0003384704,0.0002407129,0.000163742,0.00001475669,0.0000281622,0.000001747703,0.0004459947],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00299039,"threshold_uncertainty_score":0.01000386,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1080656000967496,"score_gpt":0.4642765626739022,"score_spread":0.3562109625771525,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}