{"id":"W4200194650","doi":"10.1212/wnl.0000000000013165","title":"Mitochondrial DNA Copy Number as a Marker and Mediator of Stroke Prognosis","year":2021,"lang":"en","type":"article","venue":"Neurology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":27,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Impact; Thrombosis and Atherosclerosis Research Institute","funders":"Canadian Institutes of Health Research","keywords":"Buffy coat; Mendelian randomization; Stroke (engine); Odds ratio; Medicine; Confidence interval; Internal medicine; Mitochondrial DNA; Genetics; Genotype; Biology; Surgery; Genetic variants; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00005644144,0.0001238539,0.0002036985,0.00002519319,0.00003415456,0.000007107093,0.0000800757,0.0003042608,0.0007288743],"category_scores_gemma":[0.0002671327,0.0001239701,0.00007719728,0.00005969452,0.0001369531,0.000002208159,0.000120339,0.0001248449,0.00004227279],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000001367069,"about_ca_system_score_gemma":0.0000933127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001048022,"about_ca_topic_score_gemma":0.00004482947,"domain_scores_codex":[0.9988813,0.0002197617,0.0002065514,0.0004093078,0.00008581916,0.0001971953],"domain_scores_gemma":[0.9994388,0.00004478491,0.00007636057,0.000246877,0.0001041107,0.0000891157],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000952395,0.00006831028,0.05578816,0.00001283907,0.00004385314,0.00005105694,0.00002795477,6.891968e-7,0.9364911,0.0003365417,0.005814579,0.0004125017],"study_design_scores_gemma":[0.001531885,0.001152996,0.005848591,0.00000225382,0.00004282475,0.0006509531,0.00001313006,0.000005959105,0.7079943,0.0001171026,0.2824847,0.0001553174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920329,0.0001797478,0.0001235002,0.000863247,0.001502851,0.0001259867,0.00003305642,0.000009954585,0.0051287],"genre_scores_gemma":[0.9922099,0.0003205485,0.001138948,0.003219474,0.0008279461,0.00004516882,0.0001033881,0.00002793441,0.002106662],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2766701,"threshold_uncertainty_score":0.7980663,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007256071084982,"score_gpt":0.238306048229038,"score_spread":0.231049977144056,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}