{"id":"W4200201077","doi":"10.1016/j.humimm.2021.11.005","title":"Role of HLA molecular mismatch in clinical practice","year":2021,"lang":"en","type":"review","venue":"Human Immunology","topic":"Renal Transplantation Outcomes and Treatments","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Manitoba Health; University of Manitoba","funders":"Canadian Institutes of Health Research","keywords":"Human leukocyte antigen; Risk stratification; Clinical Practice; Categorization; Transplantation; Medicine; Biomarker; Intensive care medicine; Risk assessment; Computational biology; Computer science; Immunology; Internal medicine; Biology; Artificial intelligence; Family medicine; Antigen; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002296909,0.0002158962,0.002080082,0.0001707412,0.00001697373,0.00000495821,0.0001117565,0.000418163,0.0001815142],"category_scores_gemma":[0.0001409001,0.0001739124,0.0005670206,0.0001707532,0.000085898,0.00002573713,0.00003528621,0.0005319562,0.00007326769],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005049792,"about_ca_system_score_gemma":0.0002289481,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006182623,"about_ca_topic_score_gemma":0.000004996117,"domain_scores_codex":[0.9978104,0.0004598692,0.001130677,0.0002997266,0.0001241765,0.0001751443],"domain_scores_gemma":[0.9986352,0.00038619,0.0004281244,0.0004289497,0.00008465112,0.00003683039],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00006859902,0.001447409,0.0005171934,0.01070885,0.003977817,0.003222012,0.0001442728,1.327423e-7,0.00006214112,0.006721002,0.00001942687,0.9731112],"study_design_scores_gemma":[0.001638609,0.0003515631,0.001184115,0.01584741,0.002540154,0.001052363,0.0000650494,1.068295e-7,0.00001684026,0.0000560187,0.977104,0.0001437436],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0004173104,0.9923859,0.000004387096,0.00003124533,0.0001099452,0.0003996901,0.000008932782,0.00001162931,0.006630918],"genre_scores_gemma":[0.0001893093,0.9979559,0.0007996093,0.00007398574,0.00002691682,0.0000385647,0.0004157723,0.00003170327,0.0004682233],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9770846,"threshold_uncertainty_score":0.7091941,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07401202821497015,"score_gpt":0.4642905272557586,"score_spread":0.3902784990407884,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}