{"id":"W4200208170","doi":"10.22159/ijls.2021.v9i6.43430","title":"BIOSIMILARS: OPPORTUNITIES, CHALLENGES, AND THE GENERAL PRINCIPLES GOVERNING THEIR DEVELOPMENT AROUND THE GLOBE","year":2021,"lang":"en","type":"article","venue":"Innovare Journal of Life Sciences","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Biosimilar; Globe; Agency (philosophy); European union; Medicine; Business; European market; International trade","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.02678489,0.0008204116,0.0008425745,0.00285051,0.002474375,0.01323933,0.001883206,0.009631991,0.005289657],"category_scores_gemma":[0.0255447,0.0006858263,0.0009632972,0.003307214,0.007685672,0.01069464,0.003469335,0.01115345,0.002482585],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004809796,"about_ca_system_score_gemma":0.01325147,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005058947,"about_ca_topic_score_gemma":0.0030272,"domain_scores_codex":[0.9757219,0.005154403,0.003591575,0.002049194,0.01211519,0.001367743],"domain_scores_gemma":[0.9793243,0.007385097,0.003354742,0.001598761,0.006660696,0.001676349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00009304641,0.0001917661,0.001409216,0.002393539,0.000035671,0.0007326471,0.001566864,0.001242187,0.005261193,0.6243334,0.07250668,0.2902339],"study_design_scores_gemma":[0.0000188697,0.0001013535,0.001157796,0.001964064,0.00001502387,0.0006018523,0.0005912493,0.000288079,0.001380621,0.05502472,0.938798,0.0000585019],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01473821,0.433861,0.04794329,0.314411,0.013009,0.0007100115,0.0008397991,0.0005709536,0.1739167],"genre_scores_gemma":[0.1080495,0.5903836,0.1139629,0.124964,0.009457557,0.0008676896,0.001204508,0.0004731199,0.05063697],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.02678489,"threshold_uncertainty_score":0.1416537,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1843391991089525,"score_gpt":0.3157121857145352,"score_spread":0.1313729866055827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}