{"id":"W4200208170","doi":"10.22159/ijls.2021.v9i6.43430","title":"BIOSIMILARS: OPPORTUNITIES, CHALLENGES, AND THE GENERAL PRINCIPLES GOVERNING THEIR DEVELOPMENT AROUND THE GLOBE","year":2021,"lang":"en","type":"article","venue":"Innovare Journal of Life Sciences","topic":"Biosimilars and Bioanalytical Methods","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Biosimilar; Globe; Agency (philosophy); European union; Medicine; Business; European market; International trade","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004455615,0.0001403222,0.0003035208,0.00005599653,0.0005626839,0.00008231075,0.0005106626,0.000104436,0.00009417654],"category_scores_gemma":[0.0006642851,0.00005726524,0.00008270342,0.0002510005,0.001706548,0.0001298616,0.0002425872,0.0003763797,0.000002203275],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002400986,"about_ca_system_score_gemma":0.0007648457,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003230831,"about_ca_topic_score_gemma":0.00002180155,"domain_scores_codex":[0.998229,0.000631105,0.0005642344,0.0001708749,0.0001439138,0.0002608324],"domain_scores_gemma":[0.9985042,0.0006291146,0.0004134129,0.0001450112,0.0002707265,0.00003754486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0008884362,0.0005237893,0.007584785,0.0001534377,0.003032696,0.000226848,0.01561184,0.00004119482,0.03256471,0.2067297,0.02871299,0.7039295],"study_design_scores_gemma":[0.0009784233,0.0001293849,0.007044356,0.0001116515,0.00004666309,0.0009668769,0.0144658,0.0000269972,0.008540289,0.001435829,0.9660939,0.0001598317],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.3633875,0.426305,0.0005230655,0.1975028,0.002309568,0.0001837321,0.00002481392,0.00001945811,0.009744081],"genre_scores_gemma":[0.9335104,0.03925135,0.009150652,0.01569252,0.0006753778,0.000005596221,0.000003404427,0.00001505941,0.001695639],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.9373809,"threshold_uncertainty_score":0.6287846,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1843391991089525,"score_gpt":0.3157121857145352,"score_spread":0.1313729866055827,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}