{"id":"W4200208311","doi":"10.1016/j.celrep.2021.110111","title":"Inflammatory macrophages exploit unconventional pro-phagocytic integrins for phagocytosis and anti-tumor immunity","year":2021,"lang":"en","type":"article","venue":"Cell Reports","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Montreal Clinical Research Institute","funders":"National Key Research and Development Program of China Stem Cell and Translational Research; National Key Research and Development Program of China; Canadian Institutes of Health Research; National Natural Science Foundation of China; Cole Foundation; Bristol-Myers Squibb Canada; Institut de Recherche Clinique De Montréal; Bristol-Myers Squibb","keywords":"Phagocytosis; Exploit; Integrin; Immunity; Cell biology; Macrophage; Inflammation; Immunology; Innate immune system; Immune system; Chemistry; Biology; Receptor; Biochemistry; Computer science; In vitro; Computer security","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004484818,0.0002537502,0.0004144964,0.0001027536,0.000356163,0.00005351383,0.00009892685,0.0001897176,0.0004306035],"category_scores_gemma":[0.000188008,0.0002446251,0.0002050488,0.0001330259,0.0001910497,0.0002332394,0.0001618988,0.0002528066,0.00003552091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008513319,"about_ca_system_score_gemma":0.0002953393,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002223643,"about_ca_topic_score_gemma":0.000007525397,"domain_scores_codex":[0.9982571,0.0001490939,0.0006528929,0.0004954839,0.00006824865,0.0003771639],"domain_scores_gemma":[0.9986782,0.0001345625,0.0003776691,0.0005008029,0.0002641434,0.00004459036],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005687108,0.0002853569,0.01372478,0.000209279,0.0001490987,0.0002023643,0.0002099865,0.00001692009,0.9797379,0.0002785987,0.001381952,0.003746912],"study_design_scores_gemma":[0.001249038,0.00008545446,0.04089599,0.00008262359,0.0001202255,0.001508511,0.0004038794,0.00004489005,0.9303452,0.0006170943,0.0243333,0.0003137597],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.985361,0.01084278,0.0007458814,0.0000774572,0.001131236,0.0004703621,0.00002142347,0.00008682369,0.001263009],"genre_scores_gemma":[0.9944056,0.0001703318,0.0002268369,0.00008292074,0.00005506097,0.0001335393,0.0003532184,0.00003414269,0.004538407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04939266,"threshold_uncertainty_score":0.9975522,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01756192622016016,"score_gpt":0.2445695504610247,"score_spread":0.2270076242408646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}