{"id":"W4200217608","doi":"10.1002/hep4.1875","title":"Aiming for Functional Cure With Established and Novel Therapies for Chronic Hepatitis B","year":2021,"lang":"en","type":"review","venue":"Hepatology Communications","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Medicine; Adverse effect; Hepatitis B virus; Chronic hepatitis; Cure rate; Hepatitis B; Immune system; Immunology; Virus; Intensive care medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0002300397,0.000409427,0.002020247,0.0002083991,0.000725207,0.00004043071,0.0003191563,0.0003656549,0.00003365767],"category_scores_gemma":[0.0003786671,0.0003328445,0.0003304628,0.0002809151,0.000568839,0.00008627294,0.0003060799,0.0004632983,0.000003993194],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002697955,"about_ca_system_score_gemma":0.001482103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003097091,"about_ca_topic_score_gemma":0.01233734,"domain_scores_codex":[0.9983101,0.0001370849,0.0005903993,0.0004751644,0.0001229249,0.0003642989],"domain_scores_gemma":[0.9950989,0.002350756,0.0003385187,0.001558468,0.0005617631,0.00009155817],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005964713,0.0006087789,0.01527462,0.02765097,0.005561119,0.00000938405,0.0005936946,3.955603e-7,0.000004676704,0.05415115,0.01919127,0.8768943],"study_design_scores_gemma":[0.0009856758,0.0002749649,0.0002563753,0.005359769,0.002665679,0.0003961325,0.00003024758,0.0001883501,5.884462e-7,0.00007958229,0.9894641,0.0002985506],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00001298225,0.9794263,0.01383989,0.002957219,0.0001439799,0.002665236,0.0006007719,0.00008443873,0.000269194],"genre_scores_gemma":[0.000244442,0.9574006,0.03234658,0.0002709354,0.0001531154,0.006220562,0.002889747,0.0000993715,0.0003746182],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9702728,"threshold_uncertainty_score":0.9999124,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.157432359708191,"score_gpt":0.3869353673339589,"score_spread":0.229503007625768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}