{"id":"W4200217608","doi":"10.1002/hep4.1875","title":"Aiming for Functional Cure With Established and Novel Therapies for Chronic Hepatitis B","year":2021,"lang":"en","type":"review","venue":"Hepatology Communications","topic":"Hepatitis B Virus Studies","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital","funders":"","keywords":"Medicine; Adverse effect; Hepatitis B virus; Chronic hepatitis; Cure rate; Hepatitis B; Immune system; Immunology; Virus; Intensive care medicine; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005915011,0.0006291305,0.001130699,0.002242901,0.0002149254,0.0007319291,0.0006042136,0.0007583863,0.004037612],"category_scores_gemma":[0.000836547,0.0001712287,0.0005715785,0.001661979,0.0002846343,0.001039838,0.0005174288,0.001205702,0.001568536],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004565387,"about_ca_system_score_gemma":0.001006884,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005947344,"about_ca_topic_score_gemma":0.001175232,"domain_scores_codex":[0.9998041,0.00004294783,0.00003786635,0.00002559953,0.00007336288,0.00001609027],"domain_scores_gemma":[0.9996862,0.0001741202,0.00004099535,0.00001058136,0.00006703681,0.00002099076],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007833092,0.00004839706,0.0001182043,0.04171944,0.0001280675,0.0001166904,0.00005772324,0.000162953,0.001499112,0.002621897,0.02299426,0.930455],"study_design_scores_gemma":[0.00002893484,0.0001144866,0.0009672586,0.01198461,0.0002762711,0.0009740439,0.00007735408,0.00006358024,0.0004656543,0.001380238,0.9836501,0.00001733611],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00009259658,0.9989352,0.00005355354,0.0001676926,0.0001486641,0.000004059383,0.00001371969,0.000005033608,0.0005796145],"genre_scores_gemma":[0.0003562654,0.9991012,0.00009392275,0.0001156244,0.00007511835,0.000004418013,0.00001738029,8.260205e-7,0.0002353235],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004037612,"threshold_uncertainty_score":0.01350719,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.157432359708191,"score_gpt":0.3869353673339589,"score_spread":0.229503007625768,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}