{"id":"W4200221642","doi":"10.1161/circresaha.121.319644","title":"IMPROvE-CED Trial: Intracoronary Autologous CD34+ Cell Therapy for Treatment of Coronary Endothelial Dysfunction in Patients With Angina and Nonobstructive Coronary Arteries","year":2021,"lang":"en","type":"article","venue":"Circulation Research","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Angina; Coronary arteries; Cell therapy; Endothelial dysfunction; Endothelial stem cell; Stable angina; Vasodilator agents; Endothelium","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009096382,0.0006530346,0.001133837,0.0002854886,0.0001664309,0.0005883856,0.0005217057,0.0008443366,0.002636676],"category_scores_gemma":[0.0006133608,0.0001545295,0.0008045319,0.0002725753,0.0003197723,0.0003080031,0.0002644102,0.001332237,0.0002801378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003286604,"about_ca_system_score_gemma":0.0003149573,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004379898,"about_ca_topic_score_gemma":0.00145755,"domain_scores_codex":[0.9997554,0.0001115561,0.00001769982,0.00003787954,0.00004089143,0.00003650793],"domain_scores_gemma":[0.999756,0.00006217455,0.00007025379,0.00002400806,0.00001810693,0.00006947498],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7950014,0.01250854,0.02053391,0.00329936,0.003977187,0.0004052691,0.0001081731,0.00258169,0.02129881,0.0009001167,0.008242989,0.1311426],"study_design_scores_gemma":[0.7769938,0.1309471,0.07571885,0.0002944014,0.002914535,0.0006264256,0.00006568913,0.00221828,0.002543163,0.0003076544,0.007329921,0.00004024913],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9800475,0.01238064,0.0005055719,0.000672398,0.0002008299,0.0007340432,0.001433189,0.00008303137,0.003942691],"genre_scores_gemma":[0.9825378,0.005098617,0.001669997,0.00137372,0.0007228057,0.001232783,0.004454453,0.0000152566,0.002894559],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002636676,"threshold_uncertainty_score":0.008820534,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04857832652190083,"score_gpt":0.3313736485441106,"score_spread":0.2827953220222097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}