{"id":"W4200221642","doi":"10.1161/circresaha.121.319644","title":"IMPROvE-CED Trial: Intracoronary Autologous CD34+ Cell Therapy for Treatment of Coronary Endothelial Dysfunction in Patients With Angina and Nonobstructive Coronary Arteries","year":2021,"lang":"en","type":"article","venue":"Circulation Research","topic":"Mesenchymal stem cell research","field":"Medicine","cited_by":45,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Angina; Coronary arteries; Cell therapy; Endothelial dysfunction; Endothelial stem cell; Stable angina; Vasodilator agents; Endothelium","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004122466,0.0001795905,0.0004323676,0.0003147866,0.0001357305,0.00002777036,0.00006025829,0.000151883,0.0002623483],"category_scores_gemma":[0.0000914398,0.0001453212,0.00007078707,0.0003913515,0.0002718545,0.0001536559,0.00003139982,0.0001624368,0.000005616223],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003474633,"about_ca_system_score_gemma":0.0005451699,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000998243,"about_ca_topic_score_gemma":0.00002600553,"domain_scores_codex":[0.9976156,0.0003368366,0.0003711269,0.0005237733,0.0007124706,0.0004402058],"domain_scores_gemma":[0.9981832,0.0005499813,0.00008309405,0.0003464978,0.000693776,0.0001434727],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.1640109,0.002371108,0.6010812,0.0002443561,0.0001305595,0.0001130622,0.001000923,0.00007806622,0.03067375,0.00004743888,0.00002707712,0.2002216],"study_design_scores_gemma":[0.07509999,0.01107235,0.9055959,0.00004321824,0.00001954776,0.00001885707,0.0003712898,0.0008399647,0.006427781,0.0001424237,0.0002504527,0.0001182426],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994252,0.0004983437,0.00005484298,0.000146383,0.0001054982,0.00422778,0.00006523756,0.00002026104,0.0006296271],"genre_scores_gemma":[0.997931,0.0002398979,0.0003075128,0.00001221906,0.00008428039,0.0004630089,0.0003163915,0.00003724727,0.0006084407],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3045147,"threshold_uncertainty_score":0.5926025,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04857832652190083,"score_gpt":0.3313736485441106,"score_spread":0.2827953220222097,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}