{"id":"W4200240003","doi":"10.1101/2021.12.14.21267750","title":"The role of sub-genomic RNA in discordant results from RT-PCR tests for COVID-19","year":2021,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Viral gastroenteritis research and epidemiology","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Calgary Laboratory Services; University of Alberta; University of Calgary","funders":"Canadian Institutes of Health Research","keywords":"Infectivity; Biology; Gene; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Coronavirus disease 2019 (COVID-19); RNA; Genome; Molecular biology; Virology; Real-time polymerase chain reaction; Genetics; Virus; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003653764,0.0008916899,0.0006760857,0.001518679,0.0004670648,0.001702987,0.0006585032,0.001293979,0.001113018],"category_scores_gemma":[0.01179637,0.0009435522,0.0005243236,0.0006480554,0.0012252,0.0003945816,0.000651419,0.0008656151,0.0007894461],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007028382,"about_ca_system_score_gemma":0.0002728665,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000895195,"about_ca_topic_score_gemma":0.0008982577,"domain_scores_codex":[0.991937,0.001457551,0.001092358,0.002034757,0.002928318,0.0005500065],"domain_scores_gemma":[0.9870403,0.007052743,0.002563301,0.0009309825,0.0021663,0.0002463484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0006254402,0.00009916014,0.04932739,0.0002456288,0.0000800891,0.001861716,0.0008500756,0.0004442952,0.9387006,0.0002357175,0.000249977,0.007279897],"study_design_scores_gemma":[0.00002572139,0.0005840797,0.09967642,0.0000828765,0.0001899109,0.007885068,0.0006795059,0.005279859,0.8811296,0.0003976289,0.004019337,0.00004999272],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9635793,0.002748443,0.02895065,0.0002714792,0.000315934,0.0001933394,0.0008479051,0.0004615349,0.002631376],"genre_scores_gemma":[0.9797602,0.000349618,0.0172976,0.0004117433,0.00006710176,0.0001017055,0.001117795,0.0001134725,0.0007806826],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003653764,"threshold_uncertainty_score":0.01932317,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05695542916176321,"score_gpt":0.3582655885097417,"score_spread":0.3013101593479784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}