{"id":"W4200252343","doi":"10.3390/cells11010076","title":"Pax-5 Protein Expression Is Regulated by Transcriptional 3′UTR Editing","year":2021,"lang":"en","type":"article","venue":"Cells","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Atlantic Cancer Research Institute; Dr. Georges-L.-Dumont University Hospital Centre; Université de Moncton","funders":"Natural Sciences and Engineering Research Council of Canada; New Brunswick Innovation Foundation; Leukemia and Lymphoma Society of Canada; Fondation de la recherche en santé du Nouveau-Brunswick; Beatrice Hunter Cancer Research Institute","keywords":"Biology; Untranslated region; Three prime untranslated region; Carcinogenesis; Polyadenylation; Gene; Regulation of gene expression; Genetics; Gene expression; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001691819,0.0002871299,0.0001831113,0.0001967739,0.0001994598,0.0003723918,0.0001575119,0.0001875694,0.0009900966],"category_scores_gemma":[0.0001841742,0.0001866124,0.0003968714,0.0001212858,0.0002775918,0.0002399528,0.000327843,0.0004335982,0.0004381206],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002626076,"about_ca_system_score_gemma":0.0001768326,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003018444,"about_ca_topic_score_gemma":0.0004131366,"domain_scores_codex":[0.9998108,0.0000303804,0.00001532411,0.0000651907,0.00004600192,0.00003232768],"domain_scores_gemma":[0.9998202,0.00004978003,0.00006776026,0.00002396236,0.0000167652,0.0000214856],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004965479,0.000003839944,0.0003969957,0.00001764567,0.00000394137,0.00005590307,0.00001427793,0.00004861967,0.9980849,0.0002236313,0.00001826624,0.001082375],"study_design_scores_gemma":[0.000008111777,0.00009326654,0.01571779,0.000009232464,0.00001739434,0.0004311752,0.00004540868,0.001534711,0.9782934,0.0002330884,0.003608153,0.000008166757],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9804324,0.003234862,0.0139776,0.0001073355,0.00003436524,0.00002157407,0.0003979667,0.0001381606,0.001655681],"genre_scores_gemma":[0.9932159,0.0007634092,0.004006267,0.00004791001,0.00001375111,0.00001991838,0.0005929903,0.00003202859,0.001307851],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009900966,"threshold_uncertainty_score":0.003312171,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004527779895279607,"score_gpt":0.2398679215202788,"score_spread":0.2353401416249992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}