{"id":"W4200252343","doi":"10.3390/cells11010076","title":"Pax-5 Protein Expression Is Regulated by Transcriptional 3′UTR Editing","year":2021,"lang":"en","type":"article","venue":"Cells","topic":"CRISPR and Genetic Engineering","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Atlantic Cancer Research Institute; Dr. Georges-L.-Dumont University Hospital Centre; Université de Moncton","funders":"Natural Sciences and Engineering Research Council of Canada; New Brunswick Innovation Foundation; Leukemia and Lymphoma Society of Canada; Fondation de la recherche en santé du Nouveau-Brunswick; Beatrice Hunter Cancer Research Institute","keywords":"Biology; Untranslated region; Three prime untranslated region; Carcinogenesis; Polyadenylation; Gene; Regulation of gene expression; Genetics; Gene expression; Messenger RNA","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004453883,0.00009033845,0.0000681023,0.000009399953,0.00004219244,0.00001632494,0.00006331849,0.000103232,0.0002056476],"category_scores_gemma":[0.000009434999,0.00009417897,0.00005726747,0.00004338574,0.00001567718,0.000001629326,0.00002956104,0.00005858027,0.00001219872],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000004613389,"about_ca_system_score_gemma":0.0000227764,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001563211,"about_ca_topic_score_gemma":8.496206e-7,"domain_scores_codex":[0.9993951,0.00001687432,0.0001120899,0.0002336115,0.00009016042,0.0001521481],"domain_scores_gemma":[0.9997019,0.000002204324,0.0000196668,0.0001749047,0.00004593282,0.00005540974],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000005422119,0.0000219445,0.00001480721,0.00001901522,0.0000089366,0.000002916777,0.00003527128,0.00007389606,0.9723539,0.000004524366,0.0268266,0.0006327509],"study_design_scores_gemma":[0.0001970315,0.00002057438,0.00005281232,0.00002406587,0.000004052211,0.000004147113,0.00003580665,0.00006861328,0.8458009,0.00001523739,0.1536823,0.00009444174],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9739547,0.003339701,0.02061683,0.0002683258,0.0002986886,0.0001261591,0.00005735784,0.0000215177,0.001316686],"genre_scores_gemma":[0.9893575,0.00006374271,0.001872687,0.0001773105,0.0003266664,0.00001387705,0.0002339915,0.00001948781,0.007934689],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1268557,"threshold_uncertainty_score":0.3840507,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004527779895279607,"score_gpt":0.2398679215202788,"score_spread":0.2353401416249992,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}