{"id":"W4200254386","doi":"10.3390/cells10123450","title":"Reprogramming Human Adult Fibroblasts into GABAergic Interneurons","year":2021,"lang":"en","type":"article","venue":"Cells","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"Medical Research Council; Hjärnfonden; Kungliga Fysiografiska Sällskapet i Lund; Lunds Universitet; National Institute for Health and Care Research; Department of Health and Social Care; Wellcome Trust; Åhlén-stiftelsen; Vetenskapsrådet; Jeanssons Stiftelser","keywords":"Reprogramming; GABAergic; Neuroscience; Biology; Gene silencing; Transcription factor; Cell type; Cell biology; Cell; Inhibitory postsynaptic potential; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003649441,0.0005792066,0.0002974804,0.0003388048,0.0001754613,0.000302204,0.0002161433,0.0002675111,0.002802286],"category_scores_gemma":[0.00016764,0.0001555837,0.0003256941,0.0002610872,0.0001372864,0.00009891946,0.0002142335,0.0003714251,0.001577153],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001067792,"about_ca_system_score_gemma":0.000188688,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005269251,"about_ca_topic_score_gemma":0.0008298209,"domain_scores_codex":[0.9996186,0.00004008417,0.00006066116,0.00008283873,0.0001488619,0.0000489247],"domain_scores_gemma":[0.9999062,0.00001748494,0.00001729479,0.00002343803,0.00002457646,0.00001102461],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005748691,0.00003987668,0.0001950497,0.0000700943,0.000006843717,0.0001257215,0.00003905627,0.00009098314,0.9929904,0.0001615472,0.0001786859,0.006044177],"study_design_scores_gemma":[0.0000230457,0.0002509895,0.001976348,0.00002006175,0.00003382263,0.0005450648,0.00002601767,0.0005184368,0.9706177,0.00007700209,0.02590089,0.00001069266],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8162749,0.006793453,0.1374002,0.0002404623,0.0005960218,0.001616845,0.009373566,0.001225786,0.02647887],"genre_scores_gemma":[0.8687215,0.007890545,0.07889803,0.0002485457,0.00008308273,0.001408544,0.01175866,0.0002547328,0.03073641],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002802286,"threshold_uncertainty_score":0.009374559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0103463331465318,"score_gpt":0.2771355925451147,"score_spread":0.2667892593985829,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}