{"id":"W4200268997","doi":"10.3390/cancers14010151","title":"BRG1 and NPM-ALK Are Co-Regulated in Anaplastic Large-Cell Lymphoma; BRG1 Is a Potential Therapeutic Target in ALCL","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"European Commission; Marie Curie; Cancer Research UK; Wellcome Trust","keywords":"Anaplastic large-cell lymphoma; Anaplastic lymphoma kinase; Cancer research; Chemistry; Nucleophosmin; Lymphoma; Biology; Medicine; Oncology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008541528,0.0001599978,0.0001934046,0.00004808373,0.00004332378,0.00002569763,0.00009110991,0.0001440021,0.00008575625],"category_scores_gemma":[0.00001413273,0.0001703805,0.00005750087,0.0001641982,0.00005199688,0.00000415218,0.00004904644,0.00007716518,0.000004202765],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000201947,"about_ca_system_score_gemma":0.0004798082,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001787172,"about_ca_topic_score_gemma":0.0006845696,"domain_scores_codex":[0.9989083,0.00005379126,0.0001980756,0.0004182831,0.0001093678,0.0003121474],"domain_scores_gemma":[0.9995831,0.000007318677,0.00006582024,0.0002244695,0.00004968774,0.00006962645],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006391812,0.0002894901,0.02279708,0.0003028114,0.0001610378,0.0002344149,0.0008701566,0.02292273,0.9310991,0.00002198138,0.007761897,0.01290013],"study_design_scores_gemma":[0.0260696,0.0004182233,0.04050006,0.0005200492,0.0001114669,0.0001405563,0.002623092,0.1174192,0.7414772,0.00062386,0.06839357,0.0017031],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9862059,0.01216164,0.0004797349,0.0001347414,0.0001631396,0.00009697823,0.00007332046,0.000009852999,0.0006747456],"genre_scores_gemma":[0.9970805,0.001021505,0.000110971,0.0009321765,0.00008683115,0.00001566534,0.0001163156,0.00002503223,0.0006110148],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1896219,"threshold_uncertainty_score":0.6947914,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006386681697948307,"score_gpt":0.2404232128039724,"score_spread":0.2340365311060241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}