{"id":"W4200268997","doi":"10.3390/cancers14010151","title":"BRG1 and NPM-ALK Are Co-Regulated in Anaplastic Large-Cell Lymphoma; BRG1 Is a Potential Therapeutic Target in ALCL","year":2021,"lang":"en","type":"article","venue":"Cancers","topic":"Chromatin Remodeling and Cancer","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"European Commission; Marie Curie; Cancer Research UK; Wellcome Trust","keywords":"Anaplastic large-cell lymphoma; Anaplastic lymphoma kinase; Cancer research; Chemistry; Nucleophosmin; Lymphoma; Biology; Medicine; Oncology; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000172577,0.0002286902,0.0002778312,0.0002605732,0.0001255486,0.0003294619,0.0001781191,0.0003689224,0.001377317],"category_scores_gemma":[0.0001178692,0.0001213643,0.0001432706,0.0002211008,0.0002147024,0.0001739485,0.0001720096,0.0005429136,0.0005294441],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003848367,"about_ca_system_score_gemma":0.0001562995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002969483,"about_ca_topic_score_gemma":0.0008648356,"domain_scores_codex":[0.9998335,0.00003413187,0.000008061096,0.00003449737,0.00005581871,0.00003393486],"domain_scores_gemma":[0.9999398,0.000008965148,0.00002226465,0.000006525258,0.000005252977,0.00001711743],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001628417,0.00003853577,0.0003970831,0.00004779354,0.000006808796,0.0001082036,0.00001201937,0.00009203989,0.9951355,0.0001654528,0.0001839091,0.003649869],"study_design_scores_gemma":[0.0001080544,0.0007094772,0.01579741,0.00001320858,0.000046329,0.001594204,0.00005241339,0.001583176,0.9636311,0.0002189096,0.01623842,0.00000732925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9670429,0.02337282,0.003417075,0.0009439203,0.0001106829,0.00005906285,0.0004592174,0.0003250856,0.004269168],"genre_scores_gemma":[0.9945691,0.001684992,0.0009678612,0.0001559918,0.0000139357,0.00002796703,0.0003258678,0.00002033673,0.002233909],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001377317,"threshold_uncertainty_score":0.004607558,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006386681697948307,"score_gpt":0.2404232128039724,"score_spread":0.2340365311060241,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}