{"id":"W4200271449","doi":"10.1210/clinem/dgab926","title":"Response to Letter to the Editor from Giovanelli and Quinton: “Distinguishing Self-limited Delayed Puberty From Permanent Hypogonadotropic Hypogonadism: How and Why?”","year":2021,"lang":"en","type":"letter","venue":"The Journal of Clinical Endocrinology & Metabolism","topic":"Hypothalamic control of reproductive hormones","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children; University of Toronto","funders":"","keywords":"Hypogonadotropic hypogonadism; Medicine; Endocrinology; Hormone","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00302733,0.001187288,0.002031231,0.001154649,0.00372226,0.003389907,0.00232164,0.04368689,0.006461604],"category_scores_gemma":[0.0273934,0.0009641061,0.001258683,0.0008877119,0.00260037,0.003007505,0.001445184,0.03668754,0.005730847],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.004537406,"about_ca_system_score_gemma":0.004310552,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006239556,"about_ca_topic_score_gemma":0.008846427,"domain_scores_codex":[0.9972371,0.0007427778,0.000384268,0.0004736193,0.0007008042,0.0004615011],"domain_scores_gemma":[0.9917495,0.004098261,0.000684095,0.0002093711,0.001810637,0.001448152],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0000632502,0.00002450191,0.0005470555,0.00005147091,0.0000169321,0.002658422,0.00008817874,0.00004160751,0.00007207332,0.0005353269,0.9925784,0.003322727],"study_design_scores_gemma":[0.0002331837,0.0001069206,0.003115488,0.0006817012,0.00007917788,0.007567379,0.0008251677,0.0006106702,0.0002959518,0.004033134,0.9823036,0.0001476977],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"commentary","genre_scores_codex":[0.0002730206,0.001292403,0.00005145589,0.9528608,0.0443116,0.00001138572,0.00003994801,0.00002332595,0.001136128],"genre_scores_gemma":[0.00305286,0.0009589998,0.0001146963,0.9228328,0.0692692,0.00002870839,0.00003033871,0.00002366732,0.003688874],"genre_candidate":"commentary","genre_consensus":"commentary","teacher_disagreement_score":0.04368689,"threshold_uncertainty_score":0.03292131,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03809584679504451,"score_gpt":0.3073754212152617,"score_spread":0.2692795744202172,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}