{"id":"W4200274519","doi":"10.1002/acn3.51476","title":"The gut microbiota in pediatric multiple sclerosis and demyelinating syndromes","year":2021,"lang":"en","type":"article","venue":"Annals of Clinical and Translational Neurology","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"Manitoba Health; Public Health Agency of Canada; University of Manitoba; SickKids Foundation; University of Toronto; Montreal Neurological Institute and Hospital; McGill University; Hospital for Sick Children; University of British Columbia","funders":"","keywords":"Lachnospiraceae; Multiple sclerosis; Medicine; Amplicon sequencing; Internal medicine; Clinically isolated syndrome; Gastroenterology; Microbiome; Gut flora; Immunology; Biology; Bioinformatics; 16S ribosomal RNA; Genetics; Gene; Firmicutes","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004315732,0.00007208176,0.0001736948,0.00002128466,0.00007668456,0.000007891727,0.00005672282,0.0001525342,0.000003385928],"category_scores_gemma":[0.0002507523,0.00005811197,0.00006368255,0.00006393898,0.0001757017,0.000003026996,0.00004275799,0.0001485893,6.614063e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":5.012437e-8,"about_ca_system_score_gemma":0.00007289525,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008789937,"about_ca_topic_score_gemma":0.0002234529,"domain_scores_codex":[0.9989203,0.000181776,0.0004487478,0.0002535317,0.00004217312,0.0001534817],"domain_scores_gemma":[0.9992392,0.0004589424,0.00008071034,0.00009158109,0.00007777139,0.00005176703],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001725955,0.00007652431,0.9715998,0.00003114884,0.00001804509,0.000004158789,0.00001599298,0.00001046238,0.01997175,0.0002986124,0.0001817934,0.007619147],"study_design_scores_gemma":[0.0006564496,0.0001371964,0.9937221,0.000004224613,0.000007052364,0.00002520368,0.0000034408,0.00005656167,0.0006794148,0.0005166578,0.004137338,0.00005433657],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9812975,0.005250917,0.00001610283,0.01321991,0.00007694204,0.00005894351,0.0000203212,0.000001790201,0.00005756948],"genre_scores_gemma":[0.9820065,0.01597608,0.0001807409,0.001681666,0.00009818626,0.00000208041,0.00002381812,0.000005659659,0.00002522231],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02212235,"threshold_uncertainty_score":0.2369737,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1220428839221954,"score_gpt":0.3690918512582125,"score_spread":0.247048967336017,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}