{"id":"W4200299476","doi":"10.2176/nmc.rc.2021-0311","title":"Randomized Clinical Trial of Endovascular Therapy for Acute Large Vessel Occlusion with Large Ischemic Core (RESCUE-Japan LIMIT): Rationale and Study Protocol","year":2021,"lang":"en","type":"article","venue":"Neurologia medico-chirurgica","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Daiichi Sankyo Europe; Japan Lifeline; Sanofi; Kowa Company; Bristol-Myers Squibb","keywords":"Medicine; Modified Rankin Scale; Randomized controlled trial; Occlusion; Internal carotid artery; Middle cerebral artery; Clinical trial; Surgery; Radiology; Internal medicine; Ischemia; Ischemic stroke","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003577724,0.0004245754,0.001872425,0.0001283109,0.0001697976,0.00002227839,0.0002617681,0.0002704396,0.0002188882],"category_scores_gemma":[0.001861212,0.0002770136,0.0005036839,0.0002742668,0.0003080806,0.00007892872,0.0003568177,0.0006142145,0.000003669418],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002005095,"about_ca_system_score_gemma":0.0003172058,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003107828,"about_ca_topic_score_gemma":0.000004396929,"domain_scores_codex":[0.9955702,0.0006425539,0.001290262,0.000977851,0.0009869772,0.0005321968],"domain_scores_gemma":[0.9964621,0.001566981,0.0004887508,0.0008881993,0.0003487665,0.0002451918],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9663564,0.006566748,0.006098629,0.0001575278,0.002665422,0.0006374102,0.0004717222,0.000001621056,0.002350882,0.0001486632,0.01299691,0.001548079],"study_design_scores_gemma":[0.8689213,0.00844707,0.001458464,0.0000573022,0.001396513,0.0001537133,0.0002740744,0.0009021162,0.001475245,0.00001724708,0.116673,0.0002239071],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8273947,0.0001692116,0.001235435,0.002155187,0.0002811064,0.1675124,0.00005508271,0.0001060178,0.001090917],"genre_scores_gemma":[0.7898145,0.001394577,0.003837663,0.007965364,0.001402225,0.1933039,0.0005444117,0.0001810736,0.001556254],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1036761,"threshold_uncertainty_score":0.9999682,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04086042957815504,"score_gpt":0.364176529348419,"score_spread":0.3233160997702639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}