{"id":"W4200299476","doi":"10.2176/nmc.rc.2021-0311","title":"Randomized Clinical Trial of Endovascular Therapy for Acute Large Vessel Occlusion with Large Ischemic Core (RESCUE-Japan LIMIT): Rationale and Study Protocol","year":2021,"lang":"en","type":"article","venue":"Neurologia medico-chirurgica","topic":"Acute Ischemic Stroke Management","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Daiichi Sankyo Europe; Japan Lifeline; Sanofi; Kowa Company; Bristol-Myers Squibb","keywords":"Medicine; Modified Rankin Scale; Randomized controlled trial; Occlusion; Internal carotid artery; Middle cerebral artery; Clinical trial; Surgery; Radiology; Internal medicine; Ischemia; Ischemic stroke","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01244213,0.005580378,0.008229245,0.001469229,0.001835519,0.00266512,0.002592748,0.005127598,0.02675108],"category_scores_gemma":[0.01277408,0.001968511,0.002816869,0.002456857,0.002403209,0.001898902,0.001475019,0.004545772,0.006607751],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001768825,"about_ca_system_score_gemma":0.00749055,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001125151,"about_ca_topic_score_gemma":0.002621624,"domain_scores_codex":[0.9911702,0.005766812,0.0006438465,0.0009080779,0.0006930878,0.0008180757],"domain_scores_gemma":[0.9961506,0.001148008,0.0007127057,0.0005293485,0.0006715285,0.0007878249],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9539111,0.01221656,0.0009913624,0.00556466,0.001535877,0.0002922045,0.0001534643,0.0009860732,0.001551343,0.002049255,0.00591253,0.01483568],"study_design_scores_gemma":[0.9575293,0.02587527,0.001152176,0.0005383488,0.001038589,0.0000830686,0.00004409809,0.0008638193,0.0002993776,0.001443178,0.01107562,0.00005703388],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"protocol","genre_gemma":"protocol","genre_scores_codex":[0.02305255,0.002597607,0.003652883,0.0009992265,0.001098933,0.9620028,0.003450524,0.0001573989,0.002988136],"genre_scores_gemma":[0.0263857,0.001442017,0.005065294,0.001241363,0.0004123489,0.9620792,0.001151443,0.0000180237,0.002204699],"genre_candidate":"protocol","genre_consensus":"protocol","teacher_disagreement_score":0.02675108,"threshold_uncertainty_score":0.08949125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04086042957815504,"score_gpt":0.364176529348419,"score_spread":0.3233160997702639,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}