{"id":"W4200312711","doi":"10.3389/fcvm.2021.800730","title":"Progressive Microstructural Deterioration Dictates Evolving Biomechanical Dysfunction in the Marfan Aorta","year":2021,"lang":"en","type":"article","venue":"Frontiers in Cardiovascular Medicine","topic":"Elasticity and Material Modeling","field":"Engineering","cited_by":39,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Heart, Lung, and Blood Institute; National Institutes of Health; School of Medicine, New York University; York University","keywords":"Marfan syndrome; Medicine; Cardiology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002345244,0.0002582434,0.0001737312,0.0004442698,0.0001230329,0.000259201,0.0001196214,0.0002703801,0.0005081032],"category_scores_gemma":[0.0001807752,0.0002308884,0.0001099986,0.000129104,0.0002114759,0.0001785156,0.0001654236,0.0002488358,0.0001062221],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001300739,"about_ca_system_score_gemma":0.00009962641,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003593164,"about_ca_topic_score_gemma":0.0005756598,"domain_scores_codex":[0.9999297,0.0000119063,0.000006848635,0.00001705368,0.00001808101,0.00001646674],"domain_scores_gemma":[0.9998633,0.00001649759,0.00007007195,0.0000114274,0.00001008678,0.00002860277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003169085,0.00006519842,0.009013958,0.00001801788,0.000004986968,0.0003708286,0.00006134254,0.0006553402,0.9876096,0.0001281576,0.00002011619,0.001735517],"study_design_scores_gemma":[0.00004560911,0.002555672,0.4592519,0.00003406634,0.00005973786,0.005421586,0.0003706006,0.02162271,0.5086387,0.0005872159,0.001372903,0.00003935187],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991385,0.00009907581,0.0006019542,0.000007962935,0.000001095288,0.000003943909,0.0000236858,0.00000885219,0.0001149878],"genre_scores_gemma":[0.9979107,0.0002643818,0.001416493,0.000008447211,0.000003682312,0.00001360222,0.00004995849,0.000003182402,0.0003295792],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0005081032,"threshold_uncertainty_score":0.001699746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007919945349581424,"score_gpt":0.2038653566135497,"score_spread":0.1959454112639682,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}