{"id":"W4200317436","doi":"10.1093/nar/gkab1173","title":"Cockayne syndrome group B protein regulates fork restart, fork progression and MRE11-dependent fork degradation in BRCA1/2-deficient cells","year":2021,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Hôpital Maisonneuve-Rosemont; Université Laval; McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Biology; Fork (system call); Cockayne syndrome; Tuning fork; Genetics; Degradation (telecommunications); Molecular biology; Gene; DNA repair; Nucleotide excision repair","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008960198,0.0004065977,0.0002798337,0.0002952452,0.0002254959,0.0002974524,0.000192566,0.0003050815,0.00139597],"category_scores_gemma":[0.00008507875,0.0002394329,0.0001915255,0.0001378726,0.0002301115,0.000121858,0.0002419679,0.000423451,0.0007227234],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003025004,"about_ca_system_score_gemma":0.0001507638,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001251553,"about_ca_topic_score_gemma":0.001586094,"domain_scores_codex":[0.9998882,0.00001684141,0.00001219158,0.00002976701,0.00002865629,0.00002442203],"domain_scores_gemma":[0.9998366,0.00001702805,0.00005089725,0.00001770154,0.00001048555,0.00006733607],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004510292,0.00001075268,0.0001623861,0.000009716468,0.000001689244,0.00004162409,0.00000554692,0.00001739118,0.9994772,0.00001892326,0.00002031886,0.000189285],"study_design_scores_gemma":[0.00003222144,0.0001873376,0.02659593,0.000007006304,0.00001247204,0.0005724418,0.00004273739,0.001444168,0.9687119,0.00004095549,0.002342718,0.00001006122],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9967175,0.001286166,0.0008520502,0.00008388752,0.00001241927,0.00001171287,0.0002899992,0.0001190273,0.0006271062],"genre_scores_gemma":[0.9955923,0.0004777192,0.0007339468,0.00003506749,0.000005083966,0.00002543722,0.0005248253,0.00002727144,0.002578262],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00139597,"threshold_uncertainty_score":0.004669964,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02151092782415184,"score_gpt":0.3054608066823766,"score_spread":0.2839498788582248,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}