{"id":"W4200321079","doi":"10.3390/nu13124550","title":"Microbiome and Human Aging: Probiotic and Prebiotic Potentials in Longevity, Skin Health and Cellular Senescence","year":2021,"lang":"en","type":"review","venue":"Nutrients","topic":"Skin Protection and Aging","field":"Medicine","cited_by":124,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Senescence; Microbiome; Biology; Proinflammatory cytokine; Skin Aging; Dysbiosis; Prebiotic; Chemokine; Gut flora; Probiotic; Proteases; Cell biology; Immunology; Inflammation; Bioinformatics; Medicine; Biochemistry; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005135858,0.0008260258,0.001239609,0.001836038,0.0002470503,0.0009956786,0.0005156221,0.00115685,0.003799352],"category_scores_gemma":[0.0007370534,0.0001966387,0.0005386254,0.001671847,0.0004235162,0.001142692,0.0008034946,0.001674803,0.001314295],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004980089,"about_ca_system_score_gemma":0.0008137582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001059731,"about_ca_topic_score_gemma":0.002047272,"domain_scores_codex":[0.9998322,0.00004313893,0.00002302995,0.00002542502,0.00005883008,0.00001739666],"domain_scores_gemma":[0.9997272,0.0001399815,0.0000370194,0.000007820422,0.00005959245,0.00002838744],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001072754,0.0000802983,0.0002206754,0.02050524,0.0001278678,0.0001467782,0.00007686314,0.0002486829,0.00170117,0.004268031,0.02273197,0.9497852],"study_design_scores_gemma":[0.00001882984,0.0001438121,0.001756554,0.009309285,0.0001607331,0.001169124,0.0001032577,0.0001126861,0.0004523529,0.003678589,0.9830724,0.00002236982],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00006315688,0.9992362,0.00004834137,0.0001682021,0.000113396,0.000001487122,0.000007371386,0.000002989972,0.0003589236],"genre_scores_gemma":[0.0005661447,0.9987601,0.0001034107,0.0001145647,0.0001029702,0.00000294346,0.00001402349,8.665261e-7,0.0003348569],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003799352,"threshold_uncertainty_score":0.01271009,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04380640482956227,"score_gpt":0.3519123637984309,"score_spread":0.3081059589688686,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}