{"id":"W4200328156","doi":"10.1016/s2152-2650(21)01578-0","title":"Poster: MM-379: MagnetisMM-1: A Study of Elranatamab (PF-06863135), a B-Cell Maturation Antigen (BCMA)-Targeted, CD3-Engaging Bispecific Antibody, for Patients with Relapsed or Refractory Multiple Myeloma (MM)","year":2021,"lang":"en","type":"article","venue":"Clinical Lymphoma Myeloma & Leukemia","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network; McGill University Health Centre; Alberta Cancer Foundation; University of Calgary","funders":"","keywords":"Bispecific antibody; Refractory (planetary science); Medicine; CD3; Antigen; Antibody; Multiple myeloma; Daratumumab; Immunology; Monoclonal antibody; Materials science; CD8","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001200323,0.001066503,0.001300033,0.0002501109,0.0004593714,0.0006976201,0.0007000997,0.001476776,0.01147444],"category_scores_gemma":[0.0005260956,0.0003439488,0.001220252,0.0001551153,0.0006103204,0.0005166277,0.0002905044,0.002575712,0.001954737],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009533419,"about_ca_system_score_gemma":0.001549907,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0011999,"about_ca_topic_score_gemma":0.002000941,"domain_scores_codex":[0.9997076,0.000102555,0.00001784214,0.00005132119,0.00003560286,0.0000849857],"domain_scores_gemma":[0.9997242,0.00003889209,0.00002565108,0.00001642826,0.000019317,0.0001755807],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5013754,0.04941673,0.00378189,0.002038856,0.002514923,0.001015446,0.000354668,0.002027102,0.09333682,0.001500822,0.04292268,0.2997147],"study_design_scores_gemma":[0.3527656,0.5479324,0.01945964,0.0002035612,0.002342595,0.001023187,0.00009944101,0.001682481,0.0241096,0.000731727,0.04957041,0.00007926971],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9531361,0.01623963,0.001495335,0.007832358,0.002507626,0.002855046,0.003127286,0.0003308966,0.01247561],"genre_scores_gemma":[0.953867,0.007669705,0.002466191,0.006618986,0.001976938,0.001388395,0.003057135,0.00009828008,0.0228573],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01147444,"threshold_uncertainty_score":0.03838581,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03499639870044778,"score_gpt":0.3336045049268814,"score_spread":0.2986081062264336,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}