{"id":"W4200328681","doi":"10.1101/2021.12.23.21268352","title":"Early Treatment with Fluvoxamine Among Patients with COVID-19: A Cost-Consequence Model","year":2021,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Pharmacological Receptor Mechanisms and Effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Impact; Achieve Life Sciences (Canada)","funders":"","keywords":"Fluvoxamine; Placebo; Medicine; Randomized controlled trial; Emergency medicine; Clinical trial; Health care; Intensive care medicine; Internal medicine; Alternative medicine; Fluoxetine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001309502,0.000471213,0.0004032076,0.00004214632,0.00009853867,0.00006679238,0.000290223,0.0003507854,0.00006631871],"category_scores_gemma":[0.00009529827,0.0003109703,0.000119863,0.00008195222,0.0001689666,0.000004896661,0.0003146482,0.0002563253,0.000004022021],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001450694,"about_ca_system_score_gemma":0.0006572037,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001663636,"about_ca_topic_score_gemma":0.0001114935,"domain_scores_codex":[0.9980143,0.0001396812,0.0002035145,0.0009581511,0.0002771775,0.0004071206],"domain_scores_gemma":[0.9985497,0.00002965806,0.0001786136,0.0005641802,0.0001649537,0.0005128998],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00325071,0.002253592,0.3494405,0.0004731978,0.001714312,0.001067747,0.0006125168,0.05486178,0.5808868,0.00003368146,0.0003601619,0.00504507],"study_design_scores_gemma":[0.01693295,0.01698296,0.122003,0.0005433809,0.001160751,0.00006084371,0.0001082843,0.009952469,0.8235411,0.0003053162,0.004497802,0.0039112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9819859,0.0001878414,0.01619907,0.00007355119,0.0001289167,0.00113561,0.0001184085,0.00003744175,0.0001332141],"genre_scores_gemma":[0.9951407,0.0002148683,0.001979552,0.0006504059,0.00007407678,0.0007248169,0.0007536613,0.00005005187,0.0004118493],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2426543,"threshold_uncertainty_score":0.9999343,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02300597914867544,"score_gpt":0.2776644158824649,"score_spread":0.2546584367337895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}