{"id":"W4200328681","doi":"10.1101/2021.12.23.21268352","title":"Early Treatment with Fluvoxamine Among Patients with COVID-19: A Cost-Consequence Model","year":2021,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Pharmacological Receptor Mechanisms and Effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Impact; Achieve Life Sciences (Canada)","funders":"","keywords":"Fluvoxamine; Placebo; Medicine; Randomized controlled trial; Emergency medicine; Clinical trial; Health care; Intensive care medicine; Internal medicine; Alternative medicine; Fluoxetine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.007724164,0.002100854,0.003474258,0.002988363,0.0006039321,0.003184387,0.002450981,0.00291817,0.008984002],"category_scores_gemma":[0.01847271,0.00133229,0.004468459,0.001984803,0.001038816,0.00171179,0.001253771,0.002605825,0.0003873945],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.005133407,"about_ca_system_score_gemma":0.004449007,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.02620891,"about_ca_topic_score_gemma":0.01170018,"domain_scores_codex":[0.9955681,0.003302847,0.0001297183,0.0004128781,0.0002482016,0.0003383206],"domain_scores_gemma":[0.9785074,0.01935378,0.0009454086,0.0001501578,0.0006106643,0.0004325297],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"simulation_or_modeling","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.0008866889,0.0001975772,0.004511278,0.0003746355,0.0007876284,0.0002238995,0.00004363732,0.9769802,0.0001061022,0.008506148,0.001374187,0.00600804],"study_design_scores_gemma":[0.0006346434,0.0002900573,0.0016221,0.0001381617,0.001274389,0.0001146962,0.00006231287,0.9794764,0.00007113483,0.01524256,0.001031493,0.00004200507],"study_design_candidate":"simulation_or_modeling","study_design_consensus":"simulation_or_modeling","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6479159,0.01187966,0.270026,0.02104048,0.0005762858,0.003634468,0.01514198,0.0004016118,0.02938355],"genre_scores_gemma":[0.9541976,0.002990371,0.03050215,0.001471034,0.0001735473,0.001955728,0.002624303,0.00003970951,0.006045464],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02620891,"threshold_uncertainty_score":0.0521127,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02300597914867544,"score_gpt":0.2776644158824649,"score_spread":0.2546584367337895,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}