{"id":"W4200329826","doi":"10.1101/2021.12.07.471584","title":"MORPHOLOGICAL DETERMINANTS OF CELL-TO-CELL VARIATIONS IN ACTION POTENTIAL DYNAMICS IN SUBSTANTIA NIGRA DOPAMINERGIC NEURONS","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Neuroscience and Neural Engineering","field":"Neuroscience","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Substantia nigra; Neuroscience; Pars compacta; Electrophysiology; Dendrite (mathematics); Axon; Bursting; Biology; Dopaminergic; Dopamine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003081918,0.0004678758,0.0005998918,0.0008426805,0.00008702254,0.0001564964,0.0007683864,0.0003535484,0.00001521051],"category_scores_gemma":[0.0004368669,0.0005284522,0.0001412347,0.002155858,0.00009923956,0.0002884022,0.0005726608,0.001011801,0.00001126291],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002871274,"about_ca_system_score_gemma":0.0002943383,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00009455946,"about_ca_topic_score_gemma":0.00005433226,"domain_scores_codex":[0.9964457,0.0002504708,0.0007802102,0.001368592,0.0004755714,0.0006795138],"domain_scores_gemma":[0.9983833,0.0001321984,0.000331399,0.0008500462,0.00009387724,0.0002091172],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002050973,0.0003469849,0.006834967,0.0001523841,8.933715e-7,0.001206555,0.000008487572,0.005217385,0.9861561,0.00005218177,0.000002150709,0.000001386711],"study_design_scores_gemma":[0.000354806,0.00006528756,0.08592937,0.0001241329,0.0000160262,2.945328e-7,0.000005258795,0.06205811,0.8510174,6.303504e-7,0.000007378264,0.0004213177],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963909,0.00003182487,0.001156106,0.00005707224,0.001579004,0.0005492189,0.0001112707,0.0001171053,0.000007534029],"genre_scores_gemma":[0.9986134,0.0002427264,0.0007940356,0.00013339,0.00005517803,0.00008169659,2.321419e-7,0.00007230305,0.000007051281],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1351387,"threshold_uncertainty_score":0.9997167,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02335653100613526,"score_gpt":0.2400958077934977,"score_spread":0.2167392767873624,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}