{"id":"W4200336763","doi":"10.1016/j.ebiom.2021.103771","title":"Interaction between dolutegravir and folate transporters and receptor in human and rodent placenta","year":2021,"lang":"en","type":"article","venue":"EBioMedicine","topic":"Folate and B Vitamins Research","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto General Hospital; University Health Network; Toronto Rehabilitation Institute; University of Toronto","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Drug Abuse Treatment Clinical Trials Network; National Institutes of Health; Canadian Institutes of Health Research; Ontario HIV Treatment Network","keywords":"Dolutegravir; Folate receptor; Placenta; Context (archaeology); Transporter; Biology; Solute carrier family; Pregnancy; Pharmacology; Fetus; Virology; Cancer cell; Gene; Biochemistry; Cancer; Genetics; Human immunodeficiency virus (HIV); Viral load","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004807945,0.0001325463,0.0002470557,0.0003765321,0.0001928361,0.0004705345,0.0003114785,0.0003071466,0.001800173],"category_scores_gemma":[0.0004816302,0.0002574022,0.0003119894,0.0002292202,0.0004348404,0.0002481844,0.0002108642,0.000390441,0.0003725143],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007096055,"about_ca_system_score_gemma":0.0004112817,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004137837,"about_ca_topic_score_gemma":0.004084034,"domain_scores_codex":[0.9997337,0.0001026869,0.00001616465,0.00005683059,0.0000474511,0.00004303029],"domain_scores_gemma":[0.9998708,0.00004314735,0.00003019384,0.00002384235,0.00001496917,0.00001704378],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001934598,0.0001566153,0.004561978,0.000460922,0.00007661986,0.0006840203,0.0002563075,0.0004376275,0.9720695,0.001215897,0.0004855922,0.01766023],"study_design_scores_gemma":[0.0002987394,0.006761089,0.06407023,0.0001829525,0.0003672333,0.01064247,0.001600707,0.006857456,0.854924,0.001231573,0.05301086,0.00005271506],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9651108,0.02232276,0.007013365,0.0005321911,0.00004871768,0.00006248027,0.0007314729,0.0001718997,0.004006413],"genre_scores_gemma":[0.9873949,0.005334327,0.003494832,0.0001271315,0.000008942799,0.00004539874,0.0005995567,0.00002731975,0.00296749],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004137837,"threshold_uncertainty_score":0.008227527,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02956678725880207,"score_gpt":0.3388764302610471,"score_spread":0.309309643002245,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}