{"id":"W4200344011","doi":"10.1038/s41598-021-02980-y","title":"Circular RNA mediated gene regulation in chronic diabetic complications","year":2021,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Circular RNAs in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University; McMaster University","funders":"Canadian Institutes of Health Research; Government of Jiangsu Province","keywords":"Gene; RNA; Circular RNA; Regulation of gene expression; Bioinformatics; Gene expression; Computational biology; Diabetes mellitus; Medicine; Biology; Genetics; Endocrinology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00037995,0.00010445,0.0001114112,0.00008093978,0.0001275046,0.00009138714,0.0001129094,0.00008597816,0.0000964725],"category_scores_gemma":[0.0003762516,0.0001198098,0.00009059915,0.0004513239,0.0001594977,0.000006405841,0.0001071649,0.00005497723,0.00002370683],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000982072,"about_ca_system_score_gemma":0.0005919167,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008009977,"about_ca_topic_score_gemma":0.0000664612,"domain_scores_codex":[0.9983409,0.0000701289,0.0003475134,0.0007421723,0.0002644423,0.0002348646],"domain_scores_gemma":[0.9983474,0.000008654916,0.0001320747,0.001216335,0.0001993131,0.00009623211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000001053536,0.00006001188,0.006150113,0.00001557923,0.00001504169,0.0001260377,0.0000150292,0.0007314252,0.9907181,0.00002262315,0.001703449,0.0004415684],"study_design_scores_gemma":[0.0001874181,0.00001096352,0.0694271,0.0000256105,0.00001756257,0.000171583,0.00001596142,0.0003868732,0.8931535,0.001943113,0.03447059,0.0001897261],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9926631,0.003850223,0.001034511,0.0001398611,0.001099338,0.0001972718,0.000007536552,0.00002128047,0.0009868364],"genre_scores_gemma":[0.9969706,0.00002597927,0.0001902581,0.00005057456,0.00008574314,0.00004156607,0.002057789,0.00001681079,0.0005607108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09756457,"threshold_uncertainty_score":0.4885701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01156870957956913,"score_gpt":0.2531037057331564,"score_spread":0.2415349961535873,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}