{"id":"W4200366135","doi":"10.1128/msystems.00507-21","title":"Changes in Gut Bacterial Translation Occur before Symptom Onset and Dysbiosis in Dextran Sodium Sulfate-Induced Murine Colitis","year":2021,"lang":"en","type":"article","venue":"mSystems","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Canada; Canadian Institute for Advanced Research","keywords":"Dysbiosis; Gut flora; Bacteria; Microbiome; Colitis; Inflammatory bowel disease; Immune system; Bacterial cell structure; Metagenomics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002229153,0.0003334402,0.0004679438,0.0006114883,0.0001718151,0.0004833093,0.0001431916,0.0005311592,0.001306935],"category_scores_gemma":[0.0002661615,0.0002477655,0.0003524549,0.0003325821,0.000408035,0.0004482363,0.0002312475,0.001187422,0.0003854011],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003979624,"about_ca_system_score_gemma":0.0002247123,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005250401,"about_ca_topic_score_gemma":0.001096868,"domain_scores_codex":[0.9997829,0.00002658423,0.00001992136,0.00005898791,0.00004831512,0.00006343905],"domain_scores_gemma":[0.9994759,0.0000364385,0.0002184411,0.00003575226,0.00003886945,0.0001946769],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000783029,0.00009772049,0.001611939,0.00003382774,0.000007978571,0.00006090968,0.00004573424,0.00006976393,0.9952309,0.00009778929,0.00006593259,0.001894544],"study_design_scores_gemma":[0.00004896425,0.002659551,0.1240618,0.0000387283,0.00004240761,0.0003368369,0.0002207199,0.001445097,0.8688162,0.0003854026,0.001913811,0.0000305139],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994346,0.001286902,0.002151156,0.0001727822,0.00004382373,0.00002304157,0.0009181197,0.0001447336,0.0009134229],"genre_scores_gemma":[0.9955123,0.0006029923,0.001358279,0.0001110387,0.00001052495,0.00003794586,0.0005931583,0.00003924747,0.001734453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001306935,"threshold_uncertainty_score":0.00437206,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01574932887337919,"score_gpt":0.255637396380695,"score_spread":0.2398880675073158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}