{"id":"W4200366135","doi":"10.1128/msystems.00507-21","title":"Changes in Gut Bacterial Translation Occur before Symptom Onset and Dysbiosis in Dextran Sodium Sulfate-Induced Murine Colitis","year":2021,"lang":"en","type":"article","venue":"mSystems","topic":"Gut microbiota and health","field":"Biochemistry, Genetics and Molecular Biology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Government of Canada; Canadian Institute for Advanced Research","keywords":"Dysbiosis; Gut flora; Bacteria; Microbiome; Colitis; Inflammatory bowel disease; Immune system; Bacterial cell structure; Metagenomics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001921298,0.0001328914,0.0002165336,0.00006771956,0.000037532,0.00002999907,0.00006002135,0.0002126708,0.00001971765],"category_scores_gemma":[0.00001337612,0.0001401222,0.00002998104,0.0001123709,0.00001646505,0.000003673597,0.00002753077,0.00008046048,0.000003047199],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003064324,"about_ca_system_score_gemma":0.00009947839,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005497713,"about_ca_topic_score_gemma":0.06822011,"domain_scores_codex":[0.9989616,0.0001396028,0.0002469218,0.0003231796,0.00005808421,0.0002705656],"domain_scores_gemma":[0.9996694,0.000008404991,0.00005002065,0.0001727959,0.00003193938,0.00006743518],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.00009188326,0.00005046756,0.03695958,0.0002044945,0.00001176584,0.00002193545,0.0006689067,5.71543e-7,0.9609134,0.000009740266,0.00007891595,0.0009882926],"study_design_scores_gemma":[0.003687039,0.0004247045,0.6550177,0.0003023659,0.00001689543,0.0001569891,0.0006810635,0.00006178351,0.3256828,0.00001431659,0.01357729,0.0003770694],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981022,0.000445188,0.000004864759,0.0006532337,0.0002874109,0.0002769232,0.0001172982,0.000007663312,0.0001052015],"genre_scores_gemma":[0.9988617,0.0001510742,0.00004245139,0.00009152407,0.0002020963,0.00002863075,0.0005195178,0.0000158522,0.00008714011],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.6352307,"threshold_uncertainty_score":0.9487824,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01574932887337919,"score_gpt":0.255637396380695,"score_spread":0.2398880675073158,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}