{"id":"W4200383795","doi":"10.3390/vaccines9121456","title":"Myelin Peptide–Mannan Conjugate Multiple Sclerosis Vaccines: Conjugation Efficacy and Stability of Vaccine Ingredient","year":2021,"lang":"en","type":"article","venue":"Vaccines","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Victoria University; General Secretariat for Research and Technology; Eli Lilly and Company","keywords":"Mannan; Peptide; Conjugate; Epitope; Peptide vaccine; Antigen; Chemistry; Biochemistry; Immunology; Biology; Polysaccharide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003105415,0.0002112249,0.00018029,0.0002138347,0.0001068285,0.0002097633,0.0001292906,0.0002876883,0.0008514041],"category_scores_gemma":[0.000491938,0.0000959451,0.0001182576,0.0001817306,0.0001509481,0.0003790603,0.0001766525,0.0002917704,0.0001784157],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002286614,"about_ca_system_score_gemma":0.0002239039,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004528576,"about_ca_topic_score_gemma":0.0003001121,"domain_scores_codex":[0.9998049,0.00004317912,0.00001697985,0.00003757916,0.00006494998,0.00003241813],"domain_scores_gemma":[0.9998127,0.00004497003,0.00005618809,0.00001733086,0.00004134481,0.00002752848],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004276714,0.00007854023,0.0005024535,0.00004811207,0.000009176912,0.00002477615,0.00003573698,0.0002621005,0.9920562,0.0001292684,0.00003716642,0.006388772],"study_design_scores_gemma":[0.00001474863,0.001467865,0.002561247,0.000004800991,0.00002113389,0.0001117053,0.000009626596,0.001306284,0.9936106,0.00005539137,0.000831584,0.000005104403],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9950588,0.002278193,0.001655765,0.00003256738,0.00001325031,0.00003235511,0.00007321598,0.0000213302,0.0008344699],"genre_scores_gemma":[0.9977182,0.0005191651,0.0008973145,0.00001417418,0.000008010894,0.00001300706,0.0001118081,0.000007123983,0.0007113311],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008514041,"threshold_uncertainty_score":0.002848208,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02816847556082991,"score_gpt":0.2413090561154441,"score_spread":0.2131405805546142,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}