{"id":"W4200387066","doi":"10.1016/j.ceca.2021.102521","title":"Modulators of TRPM7 and its potential as a drug target for brain tumours","year":2021,"lang":"en","type":"review","venue":"Cell Calcium","topic":"Magnesium in Health and Disease","field":"Nursing","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Canada Research Chairs","funders":"Canadian Institutes of Health Research","keywords":"TRPM7; Context (archaeology); Drug; Ion channel; Drug development; Cancer research; Neuroscience; Biology; Human brain; Transient receptor potential channel; Pharmacology; Cell biology; Medicine; Receptor; Internal medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004684011,0.0006524822,0.001390137,0.001851459,0.0002088343,0.0007543291,0.0007953081,0.001120216,0.004128699],"category_scores_gemma":[0.0008362309,0.0001968073,0.0005403757,0.001486625,0.0003800405,0.0007907825,0.0005433189,0.001633283,0.00160191],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004732575,"about_ca_system_score_gemma":0.0007429941,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009734695,"about_ca_topic_score_gemma":0.002526847,"domain_scores_codex":[0.9998608,0.00002574848,0.0000228447,0.00002268614,0.00005218124,0.00001568629],"domain_scores_gemma":[0.9997365,0.0001360818,0.00004998536,0.000005766317,0.00005474682,0.00001706818],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002227273,0.0001095105,0.0001556086,0.02133455,0.0001518936,0.0002047108,0.0000641372,0.0003104152,0.002827578,0.003508596,0.02813237,0.942978],"study_design_scores_gemma":[0.000112358,0.0003535487,0.0009148784,0.004570888,0.0003100901,0.001025607,0.00006252918,0.0001994724,0.001032018,0.002281933,0.9891116,0.00002511381],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001371206,0.9986567,0.0000843904,0.0002367968,0.000147557,0.000004147195,0.00001726264,0.000006016567,0.000709874],"genre_scores_gemma":[0.001214824,0.9977205,0.0001622675,0.0002040377,0.0001546864,0.000007637624,0.00002786152,0.000001366262,0.0005068316],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004128699,"threshold_uncertainty_score":0.01381189,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03494567069037374,"score_gpt":0.3510313214601404,"score_spread":0.3160856507697667,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}