{"id":"W4200403175","doi":"10.1101/2021.12.23.473878","title":"Regulation of the PKD2 Channel Function by TACAN","year":2021,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Genetic and Kidney Cyst Diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Chemistry; Cell biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009498524,0.0001971946,0.0001547739,0.0001141193,0.0001677138,0.0002396254,0.0001862549,0.0002031539,0.0008456885],"category_scores_gemma":[0.0001249128,0.00007247275,0.0002113926,0.00008623494,0.0001915706,0.0001904297,0.0001645732,0.0003689781,0.0002015646],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002753093,"about_ca_system_score_gemma":0.0001331025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003373355,"about_ca_topic_score_gemma":0.0004029472,"domain_scores_codex":[0.999913,0.00001498986,0.00001262213,0.00001727749,0.00002560837,0.00001649947],"domain_scores_gemma":[0.9999269,0.00001605965,0.00001850627,0.000006804586,0.00001059609,0.00002113897],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005875068,0.00001046003,0.0001091609,0.00002301878,0.000002583748,0.00005586832,0.000004788828,0.00003283346,0.9993221,0.00006349593,0.00002407709,0.0002928664],"study_design_scores_gemma":[0.00002192302,0.00008026113,0.00353963,0.000003519346,0.00001081109,0.0003583759,0.00001582041,0.0022509,0.9921143,0.00004505021,0.001553666,0.000005819711],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9949059,0.001071234,0.002564905,0.00008899959,0.00004032307,0.00001506647,0.00020816,0.00004560226,0.001059816],"genre_scores_gemma":[0.9979533,0.0002394871,0.0008927854,0.00003712975,0.000005379147,0.00001464838,0.0001717129,0.000006774777,0.0006788402],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008456885,"threshold_uncertainty_score":0.002829134,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006247386064022495,"score_gpt":0.1890059891935224,"score_spread":0.1827586031294998,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}