{"id":"W4200414711","doi":"10.1038/s41392-021-00852-5","title":"SARS-CoV-2 Omicron strain exhibits potent capabilities for immune evasion and viral entrance","year":2021,"lang":"en","type":"letter","venue":"Signal Transduction and Targeted Therapy","topic":"SARS-CoV-2 and COVID-19 Research","field":"Medicine","cited_by":288,"is_retracted":false,"has_abstract":false,"ca_institutions":"Institute of Infection and Immunity","funders":"Fundamental Research Funds for the Central Universities; National Key Research and Development Program of China; Sun Yat-sen University; National Natural Science Foundation of China","keywords":"Evasion (ethics); Virology; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); Strain (injury); Coronavirus disease 2019 (COVID-19); Immune system; 2019-20 coronavirus outbreak; Immune escape; Biology; Immunology; Medicine; Pathology; Infectious disease (medical specialty)","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003775577,0.0005246616,0.0007989287,0.0002680592,0.000227163,0.0001109962,0.000114925,0.0007319301,0.00007053956],"category_scores_gemma":[0.00001736068,0.000457976,0.0003689155,0.0001748299,0.0003425582,0.0001456523,0.00001252506,0.001240185,0.000003057203],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001101758,"about_ca_system_score_gemma":0.0002657058,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001348571,"about_ca_topic_score_gemma":0.00001063262,"domain_scores_codex":[0.9972755,0.0002006304,0.0005220953,0.0008677578,0.0005057566,0.000628253],"domain_scores_gemma":[0.999162,0.000131251,0.0001067989,0.0003143465,0.0002444135,0.00004119023],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001499428,0.0001272568,0.00005128627,0.0008653171,0.0003288075,0.00008225472,0.0009571569,2.586409e-7,0.9665509,0.0000229361,0.006944996,0.02256933],"study_design_scores_gemma":[0.003570109,0.0007038736,0.00014734,0.0001939799,0.00006693212,0.0001216348,0.0001656526,0.00004669292,0.5811682,0.0004641943,0.4130428,0.0003086726],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"commentary","genre_scores_codex":[0.8316427,0.04092908,0.001707887,0.1215964,0.000764898,0.002641819,0.0004325227,0.0001566207,0.0001280671],"genre_scores_gemma":[0.242743,0.003314312,0.0005907733,0.7475029,0.004081771,0.0003974103,0.0008036834,0.000226923,0.0003392849],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.6259064,"threshold_uncertainty_score":0.9997872,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04435947455376119,"score_gpt":0.3068261158400545,"score_spread":0.2624666412862933,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}