{"id":"W4200431462","doi":"10.1002/bies.202100152","title":"Rho GTPases: Non‐canonical regulation by cysteine oxidation","year":2021,"lang":"en","type":"review","venue":"BioEssays","topic":"Protein Kinase Regulation and GTPase Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Toronto Metropolitan University","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Ryerson University","keywords":"GTPase; Cell biology; Phosphorylation; Cysteine; CDC42; Biochemistry; Chemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003124629,0.0007088445,0.0008129803,0.00146237,0.0001977431,0.0006801005,0.0005379907,0.0007298618,0.002001193],"category_scores_gemma":[0.0003207371,0.0002334421,0.0002720156,0.001469112,0.0003334977,0.0008181371,0.0005254804,0.001181707,0.001587537],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005607354,"about_ca_system_score_gemma":0.000677775,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006941176,"about_ca_topic_score_gemma":0.0009694586,"domain_scores_codex":[0.9998825,0.00001721823,0.00001399156,0.00002720097,0.00004601128,0.00001314834],"domain_scores_gemma":[0.9998682,0.00004155587,0.00002262746,0.000005054214,0.00004660446,0.00001596242],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001437145,0.0000546589,0.0001844785,0.01494993,0.00007723725,0.000257152,0.00005992386,0.0004234368,0.01079095,0.005817452,0.02937293,0.9378683],"study_design_scores_gemma":[0.00001496781,0.00009021531,0.0008803674,0.001325395,0.00006807914,0.0008674396,0.00003062889,0.000104361,0.002409812,0.001885015,0.9923063,0.00001745536],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0002068935,0.9983295,0.0001296532,0.0001829786,0.000164135,0.000002553467,0.00001582128,0.000006682944,0.000961876],"genre_scores_gemma":[0.001385699,0.997277,0.0001353451,0.0001318921,0.0001285744,0.000005297454,0.00003000797,0.000001485075,0.0009046611],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002001193,"threshold_uncertainty_score":0.006694674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02309283680546113,"score_gpt":0.3091869158354464,"score_spread":0.2860940790299853,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}